Kowalczyk Edward, Kopff Anna, Niedworok Jan, Kopff Maria, Jankowski Andrzej
Department of Pharmacology, Basic Sciences Institute, Military Medical Academy, Łódź, Poland.
Kardiol Pol. 2002 Oct;57(10):332-6.
Anthocyanins are one of the most important water-soluble plant pigments. They belong to flavonoids and are derivatives of 2-phenylo-benzo-gamma pyren. They have antioxidant and anti-inflammatory properties and, therefore, may be potentially used to combat oxidative stress, frequently present in cardiovascular diseases.
To assess the effects of anthocyanins from chokeberry (Aronia Melanocarpa) on some parameters of oxidation-reduction balance in an animal model.
Of 20 male Wistar rats, 10 received for 3 months pure water, and the other rats 10-100 mg/l of anthocyanins from Aronia melanocarpa. Afterwards, blood samples were collected for assessment of the (1) content of substances reacting with thiobarbitural--TBARS, (2) antioxidant status and glutathione peroxidase activity, (3) concentration of sulphydryl groups, and (4) nitrite concentration.
Anthocyanins significantly reduced the content of TBARS and thiol protein groups and non-significantly increased glutathione peroxidase activity, total content of antioxidants and nitrite concentration.
Anthocyanins from chokeberry decrease lipid peroxidation which may be potentially used to combat oxidative stress.
花青素是最重要的水溶性植物色素之一。它们属于黄酮类化合物，是2-苯基苯并γ-吡喃的衍生物。它们具有抗氧化和抗炎特性，因此可能潜在地用于对抗心血管疾病中经常出现的氧化应激。
评估黑果腺肋花楸（Aronia Melanocarpa）中的花青素对动物模型氧化还原平衡某些参数的影响。
20只雄性Wistar大鼠中，10只饮用3个月的纯水，另外10只饮用含10 - 100 mg/l黑果腺肋花楸花青素的水。之后，采集血样以评估：（1）与硫代巴比妥酸反应的物质含量——TBARS；（2）抗氧化状态和谷胱甘肽过氧化物酶活性；（3）巯基浓度；（4）亚硝酸盐浓度。
花青素显著降低了TBARS和硫醇蛋白基团的含量，非显著增加了谷胱甘肽过氧化物酶活性、抗氧化剂总含量和亚硝酸盐浓度。
黑果腺肋花楸中的花青素可降低脂质过氧化，这可能潜在地用于对抗氧化应激。
