Löw M, Bühler C, Mester U
Augenklinik der Bundesknappschaft, Sulzbach/Saar.
Ophthalmologe. 2003 Jul;100(7):539-44. doi: 10.1007/s00347-002-0769-8. Epub 2003 Jun 25.
The aim of this study was to determine the efficacy of three viscoelastics of different viscosities in preventing early postoperative complications after trabeculectomy (TE) and phacotrabeculectomy (PT).
One hundred seventy-one eyes of 149 consecutive patients underwent TE or PT. In all cases, Healon, Healon GV, or Healon 5 was instilled in the anterior chamber at the beginning of surgery and left there at the end.
Four hours postoperatively, the mean intraocular pressure (IOP) in all groups was below 13 mmHg (27.4 mmHg preoperatively) and did not rise above 13 mmHg in the first postoperative week. Postoperative IOP spikes did not occur in any group. Healon remained in the anterior chamber up to 4 days after surgery, Healon GV up to 6 days, and Healon 5 up to 9 days. Characteristic early postoperative complications of filtering procedures, such as choroidal detachment, shallow anterior chamber, iridocorneal contact, hyphema, and bleb failure, were not observed in our patients.
All three viscoelastics reduced early postoperative complications with comparable efficacy and without IOP spikes.
本研究的目的是确定三种不同粘度的粘弹剂在预防小梁切除术（TE）和白内障小梁切除术（PT）术后早期并发症方面的疗效。
149例连续患者的171只眼接受了TE或PT。在所有病例中，手术开始时在前房内滴注Healon、Healon GV或Healon 5，并在手术结束时留在前房内。
术后4小时，所有组的平均眼压（IOP）均低于13 mmHg（术前为27.4 mmHg），且在术后第一周未升至13 mmHg以上。任何组均未出现术后眼压峰值。Healon在术后4天内留在前房，Healon GV在术后6天内留在前房，Healon 5在术后9天内留在前房。在我们的患者中未观察到滤过手术典型的早期术后并发症，如脉络膜脱离、前房变浅、虹膜角膜接触、前房积血和滤过泡失败。
所有三种粘弹剂均可降低术后早期并发症，疗效相当，且无眼压峰值。
