Stehle P, Dubuis O, So A, Dudler J
Department of Rheumatology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.
Ann Rheum Dis. 2003 Sep;62(9):894-6. doi: 10.1136/ard.62.9.894.
Rat bite fever is a rarely reported acute febrile bacterial illness caused by Streptobacillus moniliformis or Spirillum minus following a rat bite. It is classically characterised by abrupt onset of fever with rigors, myalgias, headache, and the appearance of a generalised maculopapular petechial skin rash. Polyarthritis complicates the course of the disease in up to 50% of infected patients, and numerous hurdles can make the diagnosis particularly difficult in the absence of fever or rash, as in the present case. A high degree of awareness is necessary to make the correct diagnosis in such cases. Diagnosis has important prognostic implications as the disease is potentially lethal, but easily treatable.
鼠咬热是一种由念珠状链杆菌或小螺菌引起的急性发热性细菌性疾病,通常在被老鼠咬伤后发生,临床报道较少。其典型特征为突然发热并伴有寒战、肌痛、头痛,以及出现全身性斑丘疹瘀点皮疹。多达50%的感染患者会出现多关节炎,使病程复杂化。在没有发热或皮疹的情况下,如本例,众多障碍会使诊断尤其困难。在这种情况下,需要高度警惕才能做出正确诊断。由于该疾病有潜在致死性但易于治疗,因此诊断具有重要的预后意义。