Highly enantioselective construction of quaternary stereocenters on beta-keto esters by phase-transfer catalytic asymmetric alkylation and Michael reaction.

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作者信息

Ooi Takashi, Miki Takashi, Taniguchi Mika, Shiraishi Misato, Takeuchi Mifune, Maruoka Keiji

机构信息

Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan.

出版信息

Angew Chem Int Ed Engl. 2003 Aug 18;42(32):3796-8. doi: 10.1002/anie.200351469.

DOI:10.1002/anie.200351469

PMID:12923847

Abstract

摘要

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Highly enantioselective construction of quaternary stereocenters on beta-keto esters by phase-transfer catalytic asymmetric alkylation and Michael reaction.

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