Mizuno T
C R Seances Soc Biol Fil. 1975;169(4):1096-8.
Our experimental analysis in organogenesis of digestive tract in embryonic chick leads to a following hypothesis. In early embryonic stages, undifferentiated endodermal epithelium is roughly determined and has an autodifferentiation potency. Cytodifferentiation but not morphogenesis like gland formation can take place in vitro in some extent in the absence of the splanchnic mesoderm. The mesoderm of the embryonic digestive tract, however, exerts its regionally specific action on the cytodifferentiation as well as morphogenesis of an indifferent epithelium.
我们对鸡胚消化道器官发生的实验分析得出了如下假设。在胚胎发育早期，未分化的内胚层上皮大致已确定，并且具有自动分化的潜能。在没有脏壁中胚层的情况下，细胞分化（而非如腺体形成那样的形态发生）在一定程度上可以在体外发生。然而，胚胎消化道的中胚层对未分化上皮的细胞分化以及形态发生发挥着区域特异性作用。
