Yasugi S
J Embryol Exp Morphol. 1984 Apr;80:137-53.
Quail allantoic endoderm was implanted into the presumptive digestive-tract area of chick embryos, and the differentiation of the endoderm was examined morphologically and immunocytochemically with antisera against pepsinogens and sucrase. The allantoic endoderm was incorporated into the host digestive organs. It often became continuous with the host endoderm and formed a chimaeric digestive-tract epithelium. It differentiated morphologically into the epithelium of the digestive organ into which it was incorporated, showing the morphological inductive ability in situ of the digestive-tract mesenchyme against the allantoic endoderm. However, the allantoic endoderm did not produce pepsinogens even when it was incorporated into the host proventricular mesenchyme and formed well-developed proventricular glands. This result indicates that the heterotypic morphogenesis of the allantoic endoderm is not necessarily accompanied by the heterotypic cytodifferentiation. In contrast, the anti-sucrase antiserum-reactive cells often differentiated in the allantoic endoderm incorporated into not only the intestine but also other organs. This confirmed our previous observation that the allantoic endoderm has a tendency to differentiate into the intestinal epithelium in the heterologous environment.
将鹌鹑尿囊内胚层植入鸡胚的假定消化道区域，并用抗胃蛋白酶原和蔗糖酶的抗血清对其进行形态学和免疫细胞化学检查。尿囊内胚层被整合到宿主消化器官中。它常常与宿主内胚层连续，并形成嵌合的消化道上皮。它在形态上分化为所整合的消化器官的上皮，显示出消化道间充质对尿囊内胚层的原位形态诱导能力。然而，即使尿囊内胚层被整合到宿主腺胃间充质中并形成发育良好的腺胃腺，它也不产生胃蛋白酶原。这一结果表明，尿囊内胚层的异型形态发生不一定伴随着异型细胞分化。相反，抗蔗糖酶抗血清反应性细胞常常在不仅整合到肠道而且还整合到其他器官的尿囊内胚层中分化。这证实了我们之前的观察结果，即尿囊内胚层在异源环境中有分化为肠上皮的倾向。
