Emmanuel Faran, Akhtar Saeed, Rahbar Mohammad H
Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
J Psychoactive Drugs. 2003 Apr-Jun;35(2):219-26. doi: 10.1080/02791072.2003.10400003.
The objective of this matched case control study was to evaluate the factors associated with heroin addiction among male heroin addicts of age 15 to 35 years in Lahore. A total of 233 heroin addicts, matched on neighborhood controls, were enrolled at a case control ratio of 1:2. Multivariate conditional logistic regression analysis was carried out to study the independent relationship of hypothesized factors with heroin addiction. The factors associated with heroin addiction were parental disharmony (i.e. occasional fights versus no fights: adjusted matched odds ratio (adj. mOR) = 4.3, 95% CI: 2.4-7.8; frequent fights versus no fights: adj. mOR = 6.0, 95% CI: 2.8-16.6), drug using peers (adj. mOR = 5.6, 95% CI, 2.6-12.1), alcohol use (adj. mOR = 4.2, 95% CI, 2.3-7.6). use of over the counter available drugs (adj. mOR = 4.1, 95% CI, 1.8-10.6), father's absence (adj. mOR = 2.9, 95% CI, 1.6-5.5), non-formal schooling of the mother (adj. mOR = 2.8, 95% CI, 1.7-4.7), non-formal schooling of the respondent (adj. mOR = 2.4, 95% CI, 1.5-3.8), and the presence of a drug user among similar age group family members (adj. mOR = 2.4, 95% CI, 1.3-4.8). It is recommended that public health strategies be formulated based on various facets of the problem revealed by this and previous research to prevent illicit drug use.
这项配对病例对照研究的目的是评估拉合尔15至35岁男性海洛因成瘾者中与海洛因成瘾相关的因素。总共233名海洛因成瘾者与社区对照进行配对，病例对照比例为1:2。进行多变量条件逻辑回归分析以研究假设因素与海洛因成瘾的独立关系。与海洛因成瘾相关的因素包括父母关系不和谐（即偶尔争吵与无争吵：调整后的配对优势比（adj. mOR）= 4.3，95%置信区间：2.4 - 7.8；频繁争吵与无争吵：adj. mOR = 6.0，95%置信区间：2.8 - 16.6）、吸毒同伴（adj. mOR = 5.6，95%置信区间，2.6 - 12.1）、饮酒（adj. mOR = 4.2，95%置信区间，2.3 - 7.6）、使用非处方可得药物（adj. mOR = 4.1，95%置信区间，1.8 - 10.6）、父亲缺席（adj. mOR = 2.9，95%置信区间，1.6 - 5.5）、母亲未接受正规教育（adj. mOR = 2.8，95%置信区间，1.7 - 4.7）、受访者未接受正规教育（adj. mOR = 2.4，95%置信区间，1.5 - 3.8）以及同龄家庭成员中有吸毒者（adj. mOR = 2.4，95%置信区间，1.3 - 4.8）。建议根据本研究及先前研究揭示的问题的各个方面制定公共卫生策略，以预防非法药物使用。
