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[乍得的沙眼:一项流行病学调查结果]

[Trachoma in Chad: results of an epidemiological survey].

作者信息

Madani Mahamat Oumar, Huguet Pierre, Mariotti Silvio Paolo, Dézoumbé Djoré, Tosi Christian, Djada Djibrim, Negrel André-Dominique

机构信息

Programme national de lutte contre la cécité, N'Djaména, Chad.

出版信息

Sante. 2003 Jan-Mar;13(1):9-15.

Abstract

A regional survey was carried out in Chad in 2000 and 2001 to estimate the prevalence and severity of trachoma. The main objectives were to describe the epidemiological pattern in terms of prevalence of inflammatory trachoma and blinding complications in two sub-samples of the population: children under 10 years of age and women over 14. Two strata were identified based on geographical criteria: two regions [Ouaddaï-Biltine, North-East] and [Lac-Kanem-Chari Baguirmi, North-West]. Random samples of thirty clusters were selected in each stratum with probability proportional to size. The simplified grading system proposed by the World Health Organisation (WHO) was used. A total of 3,952 children and 2,492 women were examined. The participation in the survey was 95% for the children sample, 92% for the women sample and the representativity of the samples was fairly good. In children under 10 years of age, the prevalence of follicular trachoma (TF) was estimated at 31.5% (IC(95%): 28.6-34.5) and that of intense inflammatory trachoma (TI) at 16.7% (IC(95%) : 14.4-19.2). The severity of the disease is high, as shown by the prevalence of trichiasis-entropion of 1.5% (IC(95%): 0.9-2.2), of central corneal opacity of 1% (IC(95%) :0.6-1.6) and of trachoma-related blindness of 0.5% (IC(95%) : 0.2-1) in women over 14. The epidemiological pattern of trachoma deserves particular attention in the field of public health in Northern Chad, where all indicators are consistently high. The national program for prevention of blindness has prepared a 3-year work plan to implement the SAFE strategy as soon as possible in these areas.

摘要

2000年和2001年在乍得进行了一项区域调查,以评估沙眼的患病率和严重程度。主要目标是根据炎症性沙眼患病率和致盲并发症情况,描述两个亚人群样本(10岁以下儿童和14岁以上女性)的流行病学模式。根据地理标准确定了两个分层:两个地区[瓦达伊-比尔廷,东北部]和[湖-卡内姆-沙里-巴吉尔米,西北部]。在每个分层中按规模比例概率抽取30个群组的随机样本。采用了世界卫生组织(WHO)提议的简化分级系统。共检查了3952名儿童和2492名女性。儿童样本的调查参与率为95%,女性样本为92%,样本的代表性相当好。在10岁以下儿童中,滤泡性沙眼(TF)的患病率估计为31.5%(95%置信区间:28.6 - 34.5),重度炎症性沙眼(TI)的患病率为16.7%(95%置信区间:14.4 - 19.2)。疾病严重程度较高,14岁以上女性中睑内翻倒睫的患病率为1.5%(95%置信区间:0.9 - 2.2),中央角膜混浊的患病率为1%(95%置信区间:0.6 - 1.6),沙眼相关失明的患病率为0.5%(95%置信区间:0.2 - 1)。在乍得北部的公共卫生领域,沙眼的流行病学模式值得特别关注,那里所有指标一直都很高。国家防盲计划已制定了一项三年工作计划,以便在这些地区尽快实施SAFE战略。

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