• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

老年高血压的治疗——故事结束了吗？

Treatment of hypertension in the elderly--the end of the story?

作者信息

Opie L H

出版信息

Cardiovasc Drugs Ther. 1992 Dec;6(6):559-62; discussion 563-4. doi: 10.1007/BF00052553.

DOI:10.1007/BF00052553
PMID:1292573
Abstract

The elderly constitute a high-risk group in which the benefit of treatment of hypertension is now obvious. The initial drug should be a low-dose diuretic, followed by a beta-blocker. At present there are no data favoring the use of an ultra low-dose diuretic, such as 12.5 mg hydrochlorothiazide, unless there is coexisting prediabetes or gout.

摘要

老年人是高血压治疗获益现已明确的高危人群。初始用药应为低剂量利尿剂，随后使用β受体阻滞剂。目前尚无数据支持使用超低剂量利尿剂，如12.5毫克氢氯噻嗪，除非同时存在糖尿病前期或痛风。

相似文献

1
Treatment of hypertension in the elderly--the end of the story?老年高血压的治疗——故事结束了吗？
Cardiovasc Drugs Ther. 1992 Dec;6(6):559-62; discussion 563-4. doi: 10.1007/BF00052553.
2
Treating essential hypertension. The first choice is usually a thiazide diuretic.治疗原发性高血压。首选药物通常是噻嗪类利尿剂。
Prescrire Int. 2014 Sep;23(152):215-20.
3
Hypertension in the elderly with coexisting benign prostatic hyperplasia.老年男性合并良性前列腺增生症时的高血压
Urology. 1999 Mar;53(3 Suppl 3a):7-12; discussion 12-3, 41-2. doi: 10.1016/s0090-4295(98)00533-0.
4
Treatment of hypertension in the elderly.老年人高血压的治疗。
Cardiovasc Drugs Ther. 1992 Dec;6(6):575-7. doi: 10.1007/BF00052557.
5
Hypertension in women and the elderly. Some puzzling and some expected findings of treatment studies.女性和老年人的高血压。治疗研究中的一些令人困惑和一些预期的发现。
Postgrad Med. 1996 Oct;100(4):58-63, 67-70. doi: 10.3810/pgm.1996.10.90.
6
Tribenzor for hypertension.用于治疗高血压的三联复方制剂
Med Lett Drugs Ther. 2010 Sep 6;52(1346):70-1.
7
Hypertension in the elderly.老年人高血压
Cardiovasc Drugs Ther. 1992 Dec;6(6):585-7. doi: 10.1007/BF00052559.
8
Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial.心血管终点维拉帕米控制起效研究（CONVINCE）试验的主要结果。
JAMA. 2003;289(16):2073-82. doi: 10.1001/jama.289.16.2073.
9
Antihypertensive efficacy and tolerability of two fixed-dose combinations of valsartan and hydrochlorothiazide compared with valsartan monotherapy in patients with stage 2 or 3 systolic hypertension: an 8-week, randomized, double-blind, parallel-group trial.缬沙坦与氢氯噻嗪两种固定剂量复方制剂与缬沙坦单药治疗对2或3期收缩期高血压患者的降压疗效及耐受性比较：一项为期8周的随机、双盲、平行组试验
Clin Ther. 2005 Jul;27(7):1013-21. doi: 10.1016/j.clinthera.2005.07.010.
10
Factorial antihypertensive study of an extended-release metoprolol and hydrochlorothiazide combination.美托洛尔缓释片与氢氯噻嗪联合使用的析因降压研究
Am J Hypertens. 2006 Dec;19(12):1217-25. doi: 10.1016/j.amjhyper.2006.05.007.

引用本文的文献

1
Individualised selection of antihypertensive therapy.抗高血压治疗的个体化选择。
Drugs. 1993;46 Suppl 2:142-8. doi: 10.2165/00003495-199300462-00023.
2
Treatment of hypertension in the elderly.老年人高血压的治疗。
Cardiovasc Drugs Ther. 1992 Dec;6(6):575-7. doi: 10.1007/BF00052557.
3
Treatment of hypertension in the elderly--what have we learned from the recent trials?老年高血压的治疗——我们从近期试验中学到了什么？

本文引用的文献

1
Treatment of mild hypertension in the elderly. A study initiated and administered by the National Heart Foundation of Australia.
Med J Aust. 1981 Oct 17;2(8):398-402.
2
Osler's maneuver and pseudohypertension.奥斯勒手法与假性高血压。
N Engl J Med. 1985 Jun 13;312(24):1548-51. doi: 10.1056/NEJM198506133122405.
3
Stroke and coronary heart disease in mild hypertension: risk factors and the value of treatment. Medical Research Council Working Party.轻度高血压患者的中风和冠心病：危险因素及治疗价值。医学研究委员会工作组
Cardiovasc Drugs Ther. 1992 Dec;6(6):571-3. doi: 10.1007/BF00052556.
4
Treatment of the older hypertensive: paradigms, practices, and proofs.老年高血压的治疗：范例、实践与证据
Cardiovasc Drugs Ther. 1992 Dec;6(6):565-9. doi: 10.1007/BF00052555.
Br Med J (Clin Res Ed). 1988 Jun 4;296(6636):1565-70.
4
Randomised trial of treatment of hypertension in elderly patients in primary care.老年患者原发性高血压治疗的随机试验
Br Med J (Clin Res Ed). 1986 Nov 1;293(6555):1145-51. doi: 10.1136/bmj.293.6555.1145.
5
MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party.医学研究委员会轻度高血压治疗试验：主要结果。医学研究委员会工作组
Br Med J (Clin Res Ed). 1985 Jul 13;291(6488):97-104. doi: 10.1136/bmj.291.6488.97.
6
Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial.欧洲老年高血压工作组试验的死亡率和发病率结果。
Lancet. 1985 Jun 15;1(8442):1349-54. doi: 10.1016/s0140-6736(85)91783-0.
7
Value of angiotensin converting enzyme inhibitors in the elderly: the example of perindopril.
Clin Exp Hypertens A. 1989;11 Suppl 2:587-603.
8
A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension.氢氯噻嗪与卡托普利对高血压患者糖脂代谢影响的比较
N Engl J Med. 1989 Sep 28;321(13):868-73. doi: 10.1056/NEJM198909283211305.
9
Insulin resistance, glucose intolerance and hyperinsulinemia in patients with hypertension.
Am J Hypertens. 1989 Jun;2(6 Pt 1):419-23. doi: 10.1093/ajh/2.6.419.
10
The recent trials for aspirin in the prevention of cardiovascular mortality.近期关于阿司匹林预防心血管疾病死亡率的试验。
Cardiovasc Drugs Ther. 1989 Jun;3(3):353-4. doi: 10.1007/BF01858107.