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嗜酸性粒细胞增多性血管淋巴样增生:一种罕见的动脉病变。

Angiolymphoid hyperplasia with eosinophilia: a rare artery lesion.

作者信息

Aurello P, Cicchini C, D'Angelo F, Di Gioia C R, D'Amati G

机构信息

Department of Surgery Pietro Valdoni, University of Rome La Sapienza, 00161 Rome, Italy.

出版信息

Anticancer Res. 2003 May-Jun;23(3C):3069-72.

Abstract

BACKGROUND

Angiolymphoid hyperplasia with eosinophilia (AHE) is a rare skin condition of unknown aetiology. The lesion seems neoplastic in nature, or at least an abnormal vasoproliferative reaction.

CASE REPORT

A 40-year-old man presented with an 18-month history of erythematous papula over the right temporal area without a history of trauma. The patient reported a history of Hodgkin lymphoma at the age of 20, treated by radiochemotherapy. A subcutaneous nodule was found on the superior branch of the right temporal artery. An echocolordoppler revealed a normal temporal artery flow with pariental thickness. An excisional biopsy was performed and the patient remained asymptomatic at 24 months. The histological diagnosis was angiolymphoid hyperplasia with eosinophilia of the temporal artery.

CONCLUSION

More appropriate studies are necessary to assess whether AHE is a manifestation of an unknown immunological disorder. If a correlation could be found between an altered immunological system and AHE, an intensive follow-up could be applied to patients. We report this case to encourage further studies to highlight potential challenges in the diagnosis and management of variants of vascular processes, such as AHE.

摘要

背景

嗜酸性粒细胞增多性血管淋巴样增生(AHE)是一种病因不明的罕见皮肤病。该病变似乎本质上是肿瘤性的,或者至少是一种异常的血管增生反应。

病例报告

一名40岁男性,右颞部出现红斑丘疹18个月,无外伤史。患者报告20岁时患霍奇金淋巴瘤,接受过放化疗。在右颞动脉上支发现一个皮下结节。彩色多普勒超声显示颞动脉血流正常,管壁厚度正常。进行了切除活检,患者在24个月时仍无症状。组织学诊断为颞动脉嗜酸性粒细胞增多性血管淋巴样增生。

结论

需要进行更合适的研究来评估AHE是否是一种未知免疫紊乱的表现。如果能在免疫系统改变与AHE之间找到关联,就可以对患者进行密切随访。我们报告此病例,以鼓励进一步研究,突出血管病变变体(如AHE)在诊断和管理方面的潜在挑战。

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