Joussen A M, Walter P, Jonescu-Cuypers C P, Koizumi K, Poulaki V, Bartz-Schmidt K U, Krieglstein G K, Kirchhof B
Department of Vitreoretinal Surgery, Center of Ophthalmology, University of Cologne, Germany.
Br J Ophthalmol. 2003 Sep;87(9):1094-102. doi: 10.1136/bjo.87.9.1094.
To report long term efficacy and complications of retinectomy as an intraocular pressure lowering procedure for intractable glaucoma.
This was a consecutive interventional case series. In 44 consecutive eyes (39 patients, 22 men and 17 women) retinectomy was performed to lower the intraocular pressure (IOP) in patients with uncontrolled IOP (>35 mm Hg for more than 4 months) despite conventional filtering surgery and drug treatment. Pars plana vitrectomy was performed and the peripheral retina was surgically excised to various degrees. The procedure was concluded by an intraocular gas tamponade of 20% C(3)F(8). Included were patients with neovascular glaucoma (12 eyes), infantile and juvenile glaucoma (three eyes), secondary glaucoma due to aphakia (13 eyes), severe ocular trauma (seven eyes), uveitis (seven eyes), and glaucoma in Ehlers-Danlos syndrome (two).
All patients underwent successful surgical retinectomy. All patients were followed for 5 years. Mean postoperative IOP after 4 years was 15.7 (SD 9.4) mm Hg, representing a decrease of IOP by 61% compared to the preoperative level (41.2 (9.4) mm Hg). In 52.3% of eyes long term regulation of IOP could be achieved without complications. Retinectomy was least effective in neovascular glaucoma because of central retinal vein occlusion (CRVO). Eyes with glaucoma secondary to uveitis showed a tendency towards low IOP levels with subsequent phthisis bulbi. The initial visual acuity of all patients was lower than 20/50 (mean 1.8 (0.8) logMAR) in the treated eye. Final visual acuity was 2.3 (0.6) logMAR. 21 out of 44 cases developed retinal complications (retinal detachment or proliferative vitreoretinopathy (PVR)) after surgery, requiring silicone tamponade in 11 eyes (52%) either for persistent low IOP or for PVR. Nine eyes developed phthisis, seven of which were enucleated during the follow up.
Long term results after retinectomy demonstrate its efficacy in otherwise intractable glaucoma. Efficacy and safety of retinectomy are dependent on the underlying disease.
报告视网膜切除术作为降低难治性青光眼眼压的手术的长期疗效和并发症。
这是一个连续的介入性病例系列。对44只连续的眼睛(39例患者,22例男性和17例女性)进行视网膜切除术,以降低尽管接受了传统滤过手术和药物治疗但眼压仍未得到控制(眼压>35 mmHg超过4个月)的患者的眼压。进行了经平坦部玻璃体切除术,并对周边视网膜进行了不同程度的手术切除。手术最后用20%的C3F8进行眼内气体填塞。纳入的患者包括新生血管性青光眼(12只眼)、婴幼儿和青少年青光眼(3只眼)、无晶状体继发性青光眼(13只眼)、严重眼外伤(7只眼)、葡萄膜炎(7只眼)以及埃勒斯-当洛综合征中的青光眼(2只眼)。
所有患者均成功进行了视网膜切除手术。所有患者均随访5年。4年后平均术后眼压为15.7(标准差9.4)mmHg,与术前水平(41.2(9.4)mmHg)相比,眼压降低了61%。52.3%的眼睛能够在无并发症的情况下实现眼压的长期控制。由于中心视网膜静脉阻塞(CRVO),视网膜切除术在新生血管性青光眼中效果最差。葡萄膜炎继发性青光眼的眼睛眼压有降低趋势,随后眼球萎缩。所有患者治疗眼的初始视力均低于20/50(平均1.8(0.8)logMAR)。最终视力为2.3(0.6)logMAR。44例患者中有21例术后出现视网膜并发症(视网膜脱离或增生性玻璃体视网膜病变(PVR)),11只眼(52%)因持续低眼压或PVR需要硅油填塞。9只眼发生眼球萎缩,其中7只在随访期间被摘除眼球。
视网膜切除术后的长期结果证明了其在其他难治性青光眼中的疗效。视网膜切除术的疗效和安全性取决于潜在疾病。