Krakowski Menahem
Nathan Kline Institute for Psychiatrric Research, Orangeburg, New York 10962, USA.
J Neuropsychiatry Clin Neurosci. 2003 Summer;15(3):294-305. doi: 10.1176/jnp.15.3.294.
There has been much interest in the role of serotonin in aggressive behavior during the past two decades, but no simple one-to-one causal relationship has been found between this biological variable and aggression. The influence of serotonin is best analyzed within a broader framework that includes consideration of its role in the inhibition of impulses, the regulation of emotions and social functioning, domains that are closely linked to aggression. Impulsivity and strong emotional states often accompany violent acts. Aggressive individuals are likely to experience general difficulties with impulse control and emotional regulation, and they show impaired social cognition and affiliation. Serotonergic dysfunction will influence aggression differently, depending on the individual's impulse control, emotional regulation, and social abilities. Yet, aggressive acts occur in a broader social context. As such, serotonergic function has an effect not only on the individual but also on the group dynamics, and it is in turn influenced by these dynamics. Whether aggression will occur when serotonin dysfunction is present will depend on individual differences as well as the overall social context.
在过去二十年里，血清素在攻击性行为中的作用备受关注，但尚未发现这一生物学变量与攻击行为之间存在简单的一对一因果关系。血清素的影响最好在一个更广泛的框架内进行分析，该框架包括考虑其在抑制冲动、调节情绪和社会功能方面的作用，这些领域与攻击行为密切相关。冲动性和强烈的情绪状态常常伴随着暴力行为。具有攻击性的个体在冲动控制和情绪调节方面可能普遍存在困难，并且他们表现出社会认知和社交能力受损。血清素功能障碍对攻击行为的影响会因个体的冲动控制、情绪调节和社交能力的不同而有所差异。然而，攻击行为发生在更广泛的社会背景中。因此，血清素功能不仅对个体有影响，对群体动态也有影响，反过来它又受到这些动态的影响。当存在血清素功能障碍时是否会发生攻击行为将取决于个体差异以及整体社会背景。
