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对患有和未患有创伤后应激障碍的前战俘内侧颞叶进行活体质子磁共振波谱分析。

In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of former prisoners of war with and without posttraumatic stress disorder.

作者信息

Brown Shelley, Freeman Thomas, Kimbrell Tim, Cardwell David, Komoroski Richard

机构信息

Mental Health Service, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA.

出版信息

J Neuropsychiatry Clin Neurosci. 2003 Summer;15(3):367-70. doi: 10.1176/jnp.15.3.367.

DOI:10.1176/jnp.15.3.367
PMID:12928515
Abstract

Proton magnetic resonance spectroscopy was used to compare medial temporal lobe (MTL) concentrations of N-acetylaspartate and choline between former prisoners of war (POWs) with and without posttraumatic stress disorder (PTSD). MTL N-acetylaspartate and reexperiencing symptoms correlated strongly in the POW subjects with PTSD, suggesting a relationship between reexperiencing symptoms and the integrity of MTL structures.

摘要

采用质子磁共振波谱法，比较了患有和未患有创伤后应激障碍（PTSD）的前战俘内侧颞叶（MTL）中N-乙酰天门冬氨酸和胆碱的浓度。在患有PTSD的战俘受试者中，MTL的N-乙酰天门冬氨酸与再次体验症状密切相关，这表明再次体验症状与MTL结构的完整性之间存在关联。

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