Sadick Neil S
Department of Dermatology, Weill Medical College of Cornell University, 772 Park Avenue, New York, NY 10021, USA.
Dermatol Surg. 2003 Sep;29(9):916-9. doi: 10.1046/j.1524-4725.2003.29250.x.
The long-pulsed 1064-nm Nd:YAG laser (employing varying spot sizes, pulse widths, and fluences) has gained popularity for treating lower extremity blue and red vessels that are less than 4 mm in diameter.
To evaluate the efficacy of high-power 50-ms 1064 Nd:YAG laser in the treatment of class I-III lower extremity vessels.
Ten female patients (mean age of 39 years) had a 5-cm2 area of veins measuring 0.2 to 3 mm in diameter treated with up to three treatment sessions using a new 1064 Nd:YAG laser, with the end point being 100% vessel clearing after three treatments. Red vessels were treated with a spot size of 1.5 mm, a fluence of 400 to 600 J/cm2, a pulse width of 30 to 50 ms; blue vessels of 1 to 3 mm were treated with a spot size of 3 mm, a fluence of 250 to 370 J/cm2, and a pulse width of 50 to 60 ms. Macrophotographic imaging evaluations by blinded observers using a quartile scale and a patient satisfaction scale were employed to evaluate results.
At month 3 after the final treatment session, 20% of all vessel types had 50% to 75% improvement. Equal clearing was noted for blue and red vessels. At month 6, 80% of patients had a greater than 75% clearing. Ninety percent of patients were highly satisfied with the treatment results at 6 months.
By varying spot size, fluence, and pulse duration, a long-wavelength 1064-nm Nd:YAG laser can achieve excellent results for treating both blue and red lower extremity vessels that are less than 3 mm in diameter.
长脉冲1064纳米钕:钇铝石榴石激光(采用不同的光斑大小、脉冲宽度和能量密度)在治疗直径小于4毫米的下肢蓝色和红色血管方面越来越受欢迎。
评估高功率50毫秒1064钕:钇铝石榴石激光治疗I - III级下肢血管的疗效。
10名女性患者(平均年龄39岁),其直径为0.2至3毫米的5平方厘米静脉区域,使用新型1064钕:钇铝石榴石激光进行多达三次治疗,终点是三次治疗后血管完全清除。红色血管采用1.5毫米光斑大小、400至600焦/平方厘米能量密度、30至50毫秒脉冲宽度进行治疗;1至3毫米的蓝色血管采用3毫米光斑大小、250至370焦/平方厘米能量密度和50至60毫秒脉冲宽度进行治疗。由不知情的观察者使用四分位数量表和患者满意度量表进行宏观摄影成像评估以评估结果。
在最后一次治疗后的第3个月,所有血管类型中有20%有50%至75%的改善。蓝色和红色血管的清除情况相同。在第6个月,80%的患者清除率大于75%。90%的患者对6个月时的治疗结果高度满意。
通过改变光斑大小、能量密度和脉冲持续时间,长波长1064纳米钕:钇铝石榴石激光在治疗直径小于3毫米的下肢蓝色和红色血管方面可取得优异效果。