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使用多同步脉冲1064纳米钕钇铝石榴石激光治疗腿部静脉扩张和网状静脉的长期效果。

Long-term results with a multiple synchronized-pulse 1064 nm Nd:YAG laser for the treatment of leg venulectasias and reticular veins.

作者信息

Sadick N S

机构信息

Joan and Sanford I. Weill Medical College and Graduate School of Medical Sciences, Cornell University, New York, NY 10021, USA.

出版信息

Dermatol Surg. 2001 Apr;27(4):365-9. doi: 10.1046/j.1524-4725.2001.00295.x.

DOI:10.1046/j.1524-4725.2001.00295.x
PMID:11298708
Abstract

BACKGROUND

The long-pulsed Nd:YAG (1064 nm) laser has been shown to be effective in the treatment of blue venulectasias and reticular veins.

OBJECTIVE

The present study examined the clinical efficacy and long-term follow-up (12 months) of patients treated with the 1064 nm Nd:YAG laser technology.

METHODS

Twenty-five female patients (mean age 37.6 years, Fitzpatrick skin types II-V) were treated with up to three treatment sessions at 6-week intervals on a 5 cm2 surface area of vessels utilizing the 1064 nm Nd:YAG laser with a circulating cooling device. Treatment parameters were vessel size 0.2-2.0 mm treated with a double pulse of 7 msec at 120 J/cm2 and vessel size 2.0-4.0 mm treated with a single pulse of 14 msec, fluence 130 J/cm2, with a spot size of 6 mm. Improvement was judged by double-blinded observer evaluation, macrophotographic imaging, optical chromatography, and a patient evaluation scale.

RESULTS

Sixty-four percent of patients treated in the present study achieved 75% or greater clearing of vessels after a maximum of three treatment sessions. Optical chromatography revealed statistically significant decreased chromophore intensity (mean blueness reduction index of 41.2b-). Sixty-four percent of patients were greatly satisfied with the results of the laser treatment. Two patients manifested vessel recurrence when examined at 6 and 12 months, respectively.

CONCLUSION

The 1064 nm Nd:YAG laser can produce effective long-term photosclerosis of blue venulectasia and reticular veins. The potential for recurrence should be recognized by the vascular laser surgeon.

摘要

背景

长脉冲Nd:YAG(1064纳米)激光已被证明在治疗蓝色静脉扩张和网状静脉方面有效。

目的

本研究检测了采用1064纳米Nd:YAG激光技术治疗患者的临床疗效及长期随访(12个月)情况。

方法

25名女性患者(平均年龄37.6岁,Fitzpatrick皮肤分型II - V型)使用带有循环冷却装置的1064纳米Nd:YAG激光,在5平方厘米的血管表面积上,每隔6周进行多达三次治疗。治疗参数为:血管直径0.2 - 2.0毫米,采用120焦耳/平方厘米的双脉冲,脉宽7毫秒;血管直径2.0 - 4.0毫米,采用单脉冲,脉宽14毫秒,能量密度130焦耳/平方厘米,光斑大小6毫米。通过双盲观察者评估、宏观摄影成像、光学色谱法以及患者评估量表来判断改善情况。

结果

本研究中接受治疗的患者,在最多三次治疗后,64%的患者血管清除率达到75%或更高。光学色谱法显示发色团强度有统计学意义的降低(平均蓝色度降低指数为41.2b - )。64%的患者对激光治疗结果非常满意。分别有两名患者在6个月和12个月检查时出现血管复发。

结论

1064纳米Nd:YAG激光可对蓝色静脉扩张和网状静脉产生有效的长期光硬化作用。血管激光外科医生应认识到复发的可能性。

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