• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

六棱菊中的桉烷衍生物及其他倍半萜类化合物。

Eudesmane derivatives and other sesquiterpenes from Laggera alata.

作者信息

Zheng Qun Xiong, Xu Zhao Jun, Sun Xian Feng, Guéritte Françoise, Cesario Michele, Sun Han Dong, Cheng Christopher H K, Hao Xiao-Jiang, Zhao Yu

机构信息

Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, and Institute of Hangzhou Commerce, Hangzhou, People's Republic of China.

出版信息

J Nat Prod. 2003 Aug;66(8):1078-81. doi: 10.1021/np0205856.

DOI:10.1021/np0205856
PMID:12932128
Abstract

Three new eudesmane sesquiterpenes, 5 beta-hydroxyilicic acid (1), 5 alpha-hydroxyl-4-epi-ilicic acid methyl ester (2), and 3 alpha-hydroxyilicic acid (3), together with 12 known sesquiterpenes were isolated from the aerial part of Laggera alata. Their structures were elucidated primarily by NMR and mass spectroscopic methods. The structures of 1 and 2 were confirmed by X-ray crystallography.

摘要

从六棱菊地上部分分离得到3个新的桉叶烷倍半萜,5β-羟基异土木香酸(1)、5α-羟基-4-表异土木香酸甲酯(2)和3α-羟基异土木香酸(3),以及12个已知倍半萜。其结构主要通过核磁共振波谱和质谱方法进行鉴定。1和2的结构通过X射线晶体学得以确证。

相似文献

1
Eudesmane derivatives and other sesquiterpenes from Laggera alata.六棱菊中的桉烷衍生物及其他倍半萜类化合物。
J Nat Prod. 2003 Aug;66(8):1078-81. doi: 10.1021/np0205856.
2
Eudesmane-type sesquiterpene derivatives from Laggera alata.大狼把蒿中的艾里莫芬烷型倍半萜衍生物。
Phytochemistry. 2013 Dec;96:201-7. doi: 10.1016/j.phytochem.2013.07.014. Epub 2013 Aug 15.
3
Laggeric acid, a novel seco-eudesmane sesquiterpenoid from Laggera crispata.拉格酸,一种从皱叶六棱菊中分离得到的新型裂环桉烷倍半萜。
J Asian Nat Prod Res. 2014;16(3):318-22. doi: 10.1080/10286020.2013.867850. Epub 2013 Dec 18.
4
Two eudesmane sesquiterpenes from Laggera pterodonta.翼齿六棱菊中的两种桉叶烷倍半萜。
J Asian Nat Prod Res. 2007 Apr-Aug;9(3-5):233-7. doi: 10.1080/10286020600603924.
5
Two eudesmane sesquiterpenes from Laggera pterodonta.翼齿六棱菊中的两种桉叶烷倍半萜。
J Asian Nat Prod Res. 2006 Jun;8(4):303-7. doi: 10.1080/10286020500034964.
6
Xanthanolides, germacranolides, and other constituents from Carpesium longifolium.长叶天名精中的呫吨酮类、吉马烷型倍半萜内酯类及其他成分。
J Nat Prod. 2003 Dec;66(12):1554-7. doi: 10.1021/np030278f.
7
A new eudesmane sesquiterpene glycosides from Liriope muscari.一种来自麦冬的新桉烷型倍半萜糖苷。
J Asian Nat Prod Res. 2012;14(5):491-5. doi: 10.1080/10286020.2012.668533. Epub 2012 Mar 16.
8
Eremophilane sesquiterpenes from Ligularia macrophylla.大叶橐吾中的雅槛蓝烷倍半萜类化合物。
J Nat Prod. 2007 Aug;70(8):1259-62. doi: 10.1021/np070113x. Epub 2007 Aug 2.
9
Four new eudesmanes from Caragana intermedia and their biological activities.中间锦鸡儿中的四种新桉烷及其生物活性。
J Nat Prod. 2004 Dec;67(12):1975-9. doi: 10.1021/np049866z.
10
New oplopane and eremophilane derivatives from Robinsonecio gerberifolius.来自格氏蓝钟花的新型奥洛烷和桉叶烷衍生物。
J Nat Prod. 2003 Feb;66(2):225-9. doi: 10.1021/np0203739.

引用本文的文献

1
Laggera alata Attenuates Inflammatory Response by Regulating Macrophage Polarization in Rheumatoid Arthritis Mice.山苦荬通过调控类风湿关节炎小鼠巨噬细胞极化缓解炎症反应。
Mol Biotechnol. 2024 Aug;66(8):1934-1941. doi: 10.1007/s12033-023-00808-w. Epub 2023 Jul 26.
2
Acetylcholinesterase inhibitory activity of sesquiterpenoids isolated from .从……中分离出的倍半萜类化合物的乙酰胆碱酯酶抑制活性。 (你提供的原文似乎不完整,“from”后面缺少具体内容)
Front Plant Sci. 2023 Feb 10;14:1074184. doi: 10.3389/fpls.2023.1074184. eCollection 2023.
3
Neuroprotective Properties of Eudesmin on a Cellular Model of Amyloid-β Peptide Toxicity.
桉脂素对淀粉样β肽毒性细胞模型的神经保护作用。
J Alzheimers Dis. 2023;94(s1):S97-S108. doi: 10.3233/JAD-220935.
4
Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus.两种天然异绿原酸异构体对温度敏感的TRPV3通道的抑制作用,用于缓解皮炎和慢性瘙痒。
Acta Pharm Sin B. 2022 Feb;12(2):723-734. doi: 10.1016/j.apsb.2021.08.002. Epub 2021 Aug 5.
5
Sesquiterpene Lactones with the 12,8-Guaianolide Skeleton from Algerian .来自阿尔及利亚. 的含 12,8-愈创内酯骨架的倍半萜内酯
Biomolecules. 2021 Jul 18;11(7):1053. doi: 10.3390/biom11071053.
6
Isochlorogenic Acid A Attenuates the Progression of Liver Fibrosis Through Regulating HMGB1/TLR4/NF-κB Signaling Pathway.异绿原酸A通过调节HMGB1/TLR4/NF-κB信号通路减轻肝纤维化进展。
Front Pharmacol. 2020 May 1;11:582. doi: 10.3389/fphar.2020.00582. eCollection 2020.
7
Protective Properties of Laggera alata Extract and its Principle Components Against d-Galactosamine-Injured Hepatocytes.六棱菊提取物及其主要成分对d-氨基半乳糖损伤肝细胞的保护作用
Sci Pharm. 2012 Apr-Jun;80(2):447-56. doi: 10.3797/scipharm.1108-16. Epub 2012 Feb 8.
8
Anti-hepatitis B virus effect and possible mechanism of action of 3,4-o-dicaffeoylquinic Acid in vitro and in vivo.3,4-o-二咖啡酰奎宁酸在体外和体内抗乙型肝炎病毒的作用及可能机制。
Evid Based Complement Alternat Med. 2012;2012:356806. doi: 10.1155/2012/356806. Epub 2012 Jun 3.
9
Biochemical conservation and evolution of germacrene A oxidase in asteraceae.倍半萜烯 A 氧化酶在菊科植物中的生物化学保存和进化。
J Biol Chem. 2010 May 28;285(22):16588-98. doi: 10.1074/jbc.M110.111757. Epub 2010 Mar 29.