拉格酸，一种从皱叶六棱菊中分离得到的新型裂环桉烷倍半萜。
Laggeric acid, a novel seco-eudesmane sesquiterpenoid from Laggera crispata.
作者信息
Qiu Yi-Hua, Yang Yan-Fang, Tan Jun-Ming, Tan Chang-Heng, Chang Jun
机构信息
a PLA 98th Hospital , Huzhou , 313000 , China.
出版信息
J Asian Nat Prod Res. 2014;16(3):318-22. doi: 10.1080/10286020.2013.867850. Epub 2013 Dec 18.
PMID:24344698
Abstract
Laggeric acid (1), a novel 4,5-seco-eudesmane sesquiterpene acid, along with 19 known compounds, was isolated from the MeOH extract of the whole plant of Laggera crispata. The structure of 1 was elucidated to be (4S,5S*,7R*,10R*)-4,5-seco-4,5-dihydroxy-11(13)-eudesmen-12-oic acid on the basis of spectroscopic analysis and a convenient Mosher's method.
摘要
从皱叶六棱菊全株的甲醇提取物中分离得到了新的4,5-断桉叶烷倍半萜酸——拉格酸（1）以及19个已知化合物。通过光谱分析和简便的莫舍尔方法确定1的结构为(4S,5S*,7R*,10R*)-4,5-断-4,5-二羟基-11(13)-桉叶烷-12-酸。
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