[Effect of different anesthesias on gastrointestinal motility after laparoscopic cholecystectomy].

OBJECTIVE

To compare the effect of three different anesthesias on gastrointestinal motility after laparoscopic cholecystectomy (LC).

METHODS

Forty-two patients undergoing LC were randomly allocated to the combined epidural-general anesthesia group (Group A, n = 14), propofol-based total intravenous anesthesia group (Group B, n = 14) and isoflurane-based inhalational-intravenous general anesthesia group (Group G, n = 14). The concentration of plasma motilin was measured; the incidence of postoperative nausea and vomiting and the first flatus time were observed; and the in-hospital day was recorded.

RESULTS

1. The concentration of plasma motilin increased significantly during the first 1 h postoperatively (P < 0.05), but it had no significant difference in the 48 h after operation (P > 0.05) in comparison with the preoperative data in the three groups. The concentration of plasma motilin in Group C was much higher than that in the other two groups during the first 1 h postoperatively (P < 0.05). 2. The incidence of postoperative nausea and vomiting was much higher in Group C than that in the other two groups during the first 6 h postoperatively (P < 0.05), but there was no significant difference in the 6 h after operation in the three groups (P > 0.05). 3. The first flatus time and in-hospital day postoperatively had no statistical difference in the three groups (P > 0.05).

CONCLUSION

Different anesthesias do not influence the recovery of intestinal motion and in-hospital day postoperatively; the combined epidural-general anesthesia and propofol-based total intravenous anesthesia may be ideal anesthesias because of the lower incidence of postoperative nausea and vomiting.