粗糙脉孢菌连锁生物钟突变体的互补分析。
Complementation analysis of linked circadian clock mutants of Neurospora crassa.
作者信息
Feldman J F, Hoyle M N
出版信息
Genetics. 1976 Jan;82(1):9-17. doi: 10.1093/genetics/82.1.9.
Abstract
A fourth mutant of Neurospora crassa, designated frq-4, has been isolated in which the period length of the circadian conidiation rhythm is shortened to 19. +/- 0.3 hours. This mutant is tightly linked to the three previously isolated frq mutants, and all four map to the right arm of linkage group VII about 10 map units from the centromere. Complementation tests suggest, but do not prove, that all four mutations are allelic, since each of the four mutants is co-dominant with the frq+ allel--i.e., heterokaryons have period lengths intermediate between the mutant and wild-type--and since heterokaryons between pairs of mutants also have period lengths intermediate between those of the two mutants.
摘要
已分离出粗糙脉孢菌的第四个突变体，命名为frq - 4，其中昼夜分生孢子节律的周期长度缩短至19±0.3小时。该突变体与之前分离出的三个frq突变体紧密连锁，所有四个突变体都定位于连锁群VII的右臂，距着丝粒约10个遗传单位。互补试验表明（但未证实）所有四个突变是等位基因，因为四个突变体中的每一个都与frq +等位基因共显性——即异核体的周期长度介于突变体和野生型之间——并且因为成对突变体之间的异核体的周期长度也介于两个突变体之间。
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