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1
Regulation of phosphate metabolism in Neurospora crassa. Characterization of regulatory mutants.粗糙脉孢菌中磷酸盐代谢的调控。调控突变体的特性
Genetics. 1973 Sep;75(1):61-73. doi: 10.1093/genetics/75.1.61.
2
Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.脉孢菌中碱性磷酸酶合成的遗传控制：在显性研究中使用部分二倍体。
Genetics. 1974 May;77(1):25-43. doi: 10.1093/genetics/77.1.25.
3
Genetic control of phosphate-metabolizing enzymes in Neurospora crassa: relationships among regulatory mutations.粗糙脉孢菌中磷酸盐代谢酶的遗传控制：调控突变之间的关系。
Genetics. 1975 Mar;79(3):419-34. doi: 10.1093/genetics/79.3.419.
4
Regulation of phosphate metabolism in Neurospora crassa: isolation of mutants deficient in ther repressible alkaline phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏碱性磷酸酶缺陷型突变体的分离
Genetics. 1974 Oct;78(2):645-59. doi: 10.1093/genetics/78.2.645.
5
The structural gene for a phosphorus-repressible phosphate permease in Neurospora crassa can complement a mutation in positive regulatory gene nuc-1.粗糙脉孢菌中一种受磷抑制的磷酸盐通透酶的结构基因可弥补正向调节基因nuc-1中的突变。
Mol Cell Biol. 1988 Mar;8(3):1376-9. doi: 10.1128/mcb.8.3.1376-1379.1988.
6
Genetic regulation of phosphate transport system II in Neurospora.粗糙脉孢菌中磷酸盐转运系统II的遗传调控
Biochim Biophys Acta. 1975 Nov 17;413(1):95-103. doi: 10.1016/0005-2736(75)90061-9.
7
Genetic and metabolic control of sulfate metabolism in Neurospora crassa: a specific permease for choline-O-sulfate.粗糙脉孢菌中硫酸盐代谢的遗传和代谢控制：一种胆碱-O-硫酸盐特异性通透酶。
Biochem Genet. 1972 Dec;7(3):219-33. doi: 10.1007/BF00484820.
8
Regulation of phosphate metabolism in Neurospora crassa: identification of the structural gene for repressible acid phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏酸性磷酸酶结构基因的鉴定。
Genetics. 1976 Oct;84(2):183-92. doi: 10.1093/genetics/84.2.183.
9
Control of the Production of orthophosphate repressible extracellular enzymes in Neurospora crassa.粗糙脉孢菌中正磷酸可阻遏的胞外酶产生的调控
Mol Gen Genet. 1977 Feb 28;151(1):5-10. doi: 10.1007/BF00446906.
10
Control of the formation of extracellular ribonuclease in Neurospora crassa.粗糙脉孢菌细胞外核糖核酸酶形成的调控
Biochim Biophys Acta. 1976 May 3;432(2):223-36. doi: 10.1016/0005-2787(76)90164-7.

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1
The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species.三个非均等“同胞”的基因组：三种木霉属物种生活方式的印记
Microbiol Mol Biol Rev. 2016 Feb 10;80(1):205-327. doi: 10.1128/MMBR.00040-15. Print 2016 Mar.
2
NUC-2, a component of the phosphate-regulated signal transduction pathway in Neurospora crassa, is an ankyrin repeat protein.NUC-2是粗糙脉孢菌中磷酸盐调节信号转导途径的一个组成部分，是一种锚蛋白重复序列蛋白。
Mol Gen Genet. 1996 Oct 28;252(6):709-16. doi: 10.1007/BF02173977.
3
Repressible extracellular phosphodiesterases showing cyclic 2',3'- and cyclic 3',5'-nucleotide phosphodiesterase activities in Neurospora crassa.在粗糙脉孢菌中表现出2',3'-环核苷酸和3',5'-环核苷酸磷酸二酯酶活性的可阻遏细胞外磷酸二酯酶。
J Bacteriol. 1983 Oct;156(1):291-300. doi: 10.1128/jb.156.1.291-300.1983.
4
Chromosomal loci of Neurospora crassa.粗糙脉孢菌的染色体位点。
Microbiol Rev. 1982 Dec;46(4):426-570. doi: 10.1128/mr.46.4.426-570.1982.
5
Regulation of phosphate metabolism in Neurospora crassa: isolation of mutants deficient in ther repressible alkaline phosphatase.粗糙脉孢菌中磷酸盐代谢的调控：可阻遏碱性磷酸酶缺陷型突变体的分离
Genetics. 1974 Oct;78(2):645-59. doi: 10.1093/genetics/78.2.645.
6
Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.脉孢菌中碱性磷酸酶合成的遗传控制：在显性研究中使用部分二倍体。
Genetics. 1974 May;77(1):25-43. doi: 10.1093/genetics/77.1.25.
7
Molecular analysis of nuc-1+, a gene controlling phosphorus acquisition in Neurospora crassa.粗糙脉孢菌中控制磷获取的基因nuc-1+的分子分析。
Mol Cell Biol. 1990 Nov;10(11):5839-48. doi: 10.1128/mcb.10.11.5839-5848.1990.
8
Enzymology and genetic regulation of a cyclic nucleotide-binding phosphodiesterase-phosphomonoesterase from Aspergillus nidulans.来自构巢曲霉的一种环核苷酸结合磷酸二酯酶-磷酸单酯酶的酶学与遗传调控
J Bacteriol. 1975 Nov;124(2):693-703. doi: 10.1128/jb.124.2.693-703.1975.
9
Implications of some genetic control mechanisms in Neurospora.粗糙脉孢菌中一些遗传控制机制的影响
Microbiol Rev. 1979 Sep;43(3):361-83. doi: 10.1128/mr.43.3.361-383.1979.
10
Control of the Production of orthophosphate repressible extracellular enzymes in Neurospora crassa.粗糙脉孢菌中正磷酸可阻遏的胞外酶产生的调控
Mol Gen Genet. 1977 Feb 28;151(1):5-10. doi: 10.1007/BF00446906.

本文引用的文献

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Nuclear Distribution in Conidia of Neurospora Heterokaryons.粗糙脉孢菌异核体分生孢子中的核分布
Genetics. 1955 Jul;40(4):438-43. doi: 10.1093/genetics/40.4.438.
2
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
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An alkaline phosphomonoesterase from Neurospora crassa.来自粗糙脉孢菌的一种碱性磷酸单酯酶。
Biochim Biophys Acta. 1961 Nov 25;54:101-9. doi: 10.1016/0006-3002(61)90942-8.
4
The role of ATP-sulfurylase in the biosynthesis of cysteine and methionine by Neurospora.ATP硫酸化酶在粗糙脉孢菌半胱氨酸和甲硫氨酸生物合成中的作用。
Arch Biochem Biophys. 1959 Oct;84:541-2. doi: 10.1016/0003-9861(59)90614-9.
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A repressible alkaline phosphatase in Neurospora crassa.粗糙脉孢菌中的一种可阻遏碱性磷酸酶。
J Biol Chem. 1966 Apr 10;241(7):1468-72.
6
Positive control by the cys-3 locus in regulation of sulfur metabolism in Neurospora.粗糙脉孢菌中cys-3基因座对硫代谢调控的阳性对照
J Mol Biol. 1968 Apr 28;33(2):423-37. doi: 10.1016/0022-2836(68)90199-x.
7
Repair of multiple defects of a regulatory mutant of Neurospora by high osmotic pressure and by reversion.通过高渗透压和回复作用修复粗糙脉孢菌调节突变体的多个缺陷。
Arch Biochem Biophys. 1968 May;125(2):532-41. doi: 10.1016/0003-9861(68)90611-5.
8
Genetic and biochemical studies of distinct sulfate permease species in different developmental stages of Neurospora crassa.粗糙脉孢菌不同发育阶段中不同硫酸盐通透酶种类的遗传与生化研究。
Arch Biochem Biophys. 1970 May;138(1):254-63. doi: 10.1016/0003-9861(70)90306-1.
9
The regulation of methionine synthesis and the nature of cystathionine gamma-synthase in Neurospora.脉孢菌中甲硫氨酸合成的调控及胱硫醚γ-合酶的性质
J Biol Chem. 1970 Apr 10;245(7):1842-55.
10
Evidence for a near limiting intracellular concentration of a regulator substance.调节物质细胞内浓度接近极限的证据。
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粗糙脉孢菌中磷酸盐代谢的调控。调控突变体的特性

Regulation of phosphate metabolism in Neurospora crassa. Characterization of regulatory mutants.

作者信息

Lehman J F, Gleason M K, Ahlgren S K, Metzenberg R L

出版信息

Genetics. 1973 Sep;75(1):61-73. doi: 10.1093/genetics/75.1.61.

DOI:10.1093/genetics/75.1.61
PMID:4271653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213002/
Abstract

A mutant of Neurospora crassa, called UW-6, differs from wild type in being partially constitutive for synthesis of a species of alkaline phosphatase, and also for a species of phosphate permease that has a high affinity for phosphate at high pH. UW-6 is possibly allelic with a mutant called nuc-2 that was previously isolated by Ishikawa. nuc-2 has the converse phenotype, in that it cannot be derepressed for either of these two activities. UW-6 is co-dominant with its wild-type allele in heterokaryons and in partial diploids. An unlinked mutant, nuc-1, is like nuc-2 in that it fails to make the alkaline phosphatase or the permease referred to above. nuc-1 is epistatic to UW-6 in the double mutant. The control of phosphorus metabolism is discussed, and is compared with some other control systems in filamentous fungi.

摘要

粗糙脉孢菌的一个突变体，称为UW - 6，与野生型的不同之处在于，它在某种碱性磷酸酶的合成上部分组成型表达，并且在高pH值下对磷酸盐具有高亲和力的某种磷酸盐通透酶的合成上也是部分组成型表达。UW - 6可能与之前由石川分离出的一个名为nuc - 2的突变体等位。nuc - 2具有相反的表型，即这两种活性中的任何一种都不能被去阻遏。UW - 6在异核体和部分二倍体中与其野生型等位基因共显性。一个不连锁的突变体nuc - 1与nuc - 2相似，即它不能产生上述碱性磷酸酶或通透酶。在双突变体中，nuc - 1对UW - 6上位。文中讨论了磷代谢的调控，并与丝状真菌中的其他一些控制系统进行了比较。