急性中耳炎患者中耳积液中头孢克洛和阿莫西林-克拉维酸水平的测定。
Measurement of cefaclor and amoxicillin-clavulanic acid levels in middle-ear fluid in patients with acute otitis media.
作者信息
Scaglione F, Caronzolo D, Pintucci J P, Fraschini F
机构信息
University of Milan, Milan, Italy.
出版信息
Antimicrob Agents Chemother. 2003 Sep;47(9):2987-9. doi: 10.1128/AAC.47.9.2987-2989.2003.
Abstract
Concentrations of cefaclor (CFC) or amoxicillin-clavulanic acid (AMX/CA) in middle-ear fluid collected preserving the stability and clearing the cell contents has been compared to those obtained using the traditional method. Sixty-seven children with effusive otitis media were treated orally with CFC (20 mg/kg of body weight) or AMX/CA (20 mg/kg) (4:1 ratio). The concentrations in cell-free fluid (C-) appear higher than those in the total fluid (C+) (as assayed traditionally).
摘要
在保持稳定性并清除细胞内容物的情况下收集的中耳液中头孢克洛（CFC）或阿莫西林 - 克拉维酸（AMX/CA）的浓度，已与使用传统方法获得的浓度进行了比较。67名分泌性中耳炎患儿口服CFC（20毫克/千克体重）或AMX/CA（20毫克/千克）（比例为4:1）进行治疗。无细胞液（C-）中的浓度似乎高于传统检测的总液（C+）中的浓度。
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