Scaglione F, Caronzolo D, Pintucci J P, Fraschini F
University of Milan, Milan, Italy.
Antimicrob Agents Chemother. 2003 Sep;47(9):2987-9. doi: 10.1128/AAC.47.9.2987-2989.2003.
Concentrations of cefaclor (CFC) or amoxicillin-clavulanic acid (AMX/CA) in middle-ear fluid collected preserving the stability and clearing the cell contents has been compared to those obtained using the traditional method. Sixty-seven children with effusive otitis media were treated orally with CFC (20 mg/kg of body weight) or AMX/CA (20 mg/kg) (4:1 ratio). The concentrations in cell-free fluid (C-) appear higher than those in the total fluid (C+) (as assayed traditionally).
在保持稳定性并清除细胞内容物的情况下收集的中耳液中头孢克洛(CFC)或阿莫西林 - 克拉维酸(AMX/CA)的浓度,已与使用传统方法获得的浓度进行了比较。67名分泌性中耳炎患儿口服CFC(20毫克/千克体重)或AMX/CA(20毫克/千克)(比例为4:1)进行治疗。无细胞液(C-)中的浓度似乎高于传统检测的总液(C+)中的浓度。