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[一例结肠癌多发肺转移经5'-脱氧氟尿苷和西咪替丁治疗后长期存活的病例]

[A case of multiple lung metastases of colon cancer with long-term survival following 5'-DFUR and cimetidine therapy].

作者信息

Fujiwara Shozo, Noguchi Tsuyoshi, Suehiro Syuji, Kikuchi Ryuichi, Noguchi Takuya, Uchida Yuzo

机构信息

Dept. of Surgery, Nagato Memorial Hospital.

出版信息

Gan To Kagaku Ryoho. 2003 Aug;30(8):1177-81.

Abstract

A 77-year-old woman treated for diabetes mellitus was admitted to our hospital for further examination of abnormal findings on chest plain radiograph. Many nodular shadows in both lung fields were seen on chest X ray and chest CT scan. Colonoscopic examination revealed a type 2 tumor in the ascending colon. We diagnosed this case as ascending colon carcinoma with multiple lung metastases, and performed right hemicolectomy and D1 lymph node dissection. After surgery, the patient was administered 5'-DFUR 600 mg/body/day, cimetidine 800 mg/body/day orally. Though no remarkable reduction of tumors was recognized, the increase of tumor size was relatively slow. The patient remains alive 3 years after surgery.

摘要

一名接受糖尿病治疗的77岁女性因胸部X线片发现异常而入院进一步检查。胸部X线和胸部CT扫描显示双肺野有许多结节状阴影。结肠镜检查发现升结肠有一个2型肿瘤。我们将该病例诊断为升结肠癌伴多发肺转移,并进行了右半结肠切除术和D1淋巴结清扫术。术后,患者口服5'-DFUR 600mg/天/人、西咪替丁800mg/天/人。虽然未观察到肿瘤明显缩小,但肿瘤大小的增加相对缓慢。患者术后3年仍存活。

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