Kaufmann Claude, Bachmann Lucas M, Thiel Michael A
Department of Ophthalmology, University of Zurich, Zurich, Switzerland.
Invest Ophthalmol Vis Sci. 2003 Sep;44(9):3790-4. doi: 10.1167/iovs.02-0946.
Thinning of the corneal stroma by laser in situ keratomileusis (LASIK) results in inaccurate low intraocular pressure (IOP) readings by Goldmann applanation tonometry (GAT). Dynamic contour tonometry (DCT) is a novel measuring technique, designed to measure IOP largely independent of corneal thickness and curvature. The purpose of this study was to compare IOP measurements using GAT and DCT in eyes undergoing LASIK for correction of myopia.
In a prospective, single-center study, central corneal thickness (CCT) and IOP were measured in patients undergoing first-time LASIK for myopia. IOP was measured before and after surgery using GAT and DCT. The untreated contralateral eyes served as paired controls.
There was good concordance between the two tonometers in 62 normal eyes before LASIK. Corneal ablation of 90.0 +/- 49.18 micro m (median +/- SD) reduced IOP readings as measured by GAT by 3.0 +/- 1.9 mm Hg (P < 0.001). In contrast, no significant change in IOP readings was recorded by DCT (-0.2 mm Hg +/- 1.5 mm Hg, P = 0.30). There was no change in IOP in the untreated control eyes as measured by GAT and DCT.
Significant decreases in IOP were recorded by GAT after LASIK for myopia. Measurements by DCT, however, did not reveal any significant changes in IOP.
准分子原位角膜磨镶术（LASIK）导致角膜基质变薄，从而使Goldmann压平眼压计（GAT）测量的眼内压（IOP）读数不准确。动态轮廓眼压计（DCT）是一种新型测量技术，旨在测量基本不受角膜厚度和曲率影响的眼压。本研究的目的是比较在接受LASIK矫正近视的眼中使用GAT和DCT测量眼压的结果。
在一项前瞻性单中心研究中，对首次接受LASIK治疗近视的患者测量中央角膜厚度（CCT）和眼压。术前和术后使用GAT和DCT测量眼压。未治疗的对侧眼作为配对对照。
LASIK术前62只正常眼中两种眼压计测量结果具有良好的一致性。90.0±49.18μm（中位数±标准差）的角膜切削使GAT测量的眼压读数降低3.0±1.9mmHg（P<0.001）。相比之下，DCT测量的眼压读数无显著变化（-0.2mmHg±1.5mmHg，P=0.30）。GAT和DCT测量未治疗对照眼的眼压无变化。
近视LASIK术后GAT测量的眼压显著降低。然而，DCT测量未显示眼压有任何显著变化。
