硫化氢对神经行为功能的影响。
Effects of hydrogen sulfide on neurobehavioral function.
作者信息
Kilburn Kaye H
机构信息
Environmental Sciences Laboratory, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
出版信息
South Med J. 2003 Jul;96(7):639-46. doi: 10.1097/01.SMJ.0000072361.86796.56.
BACKGROUND
Nineteen hydrogen sulfide (H2S)-exposed patients were compared with 202 unexposed subjects. This 1997-to-2001 case-referent series was compared with 16 previous (1991-1996) case-referent patients.
METHODS
New patients were bystanders of H2S exposure and none had been unconscious. In contrast, 13 members of the prior group were exposed at work and 7 had been unconscious. The three groups were compared on the basis of 8 physiologic and 12 psychological measurements. Observed measurements were compared with predicted ones after adjusting for age, sex, educational attainment (years), and other significant factors (observed/predicted x 100).
RESULTS
The new group performed poorly compared with unexposed controls and were similar to the first group on balance, reaction time, color discrimination, visual performance, hearing, Culture Fair, digit symbol, vocabulary, verbal recall, peg placement, trail making A and B, and information.
CONCLUSION
H2S impairments associated with H2S were similar in 19 workers (44% had been unconscious) and in 16 bystanders who had not been unconscious.
背景
将19名硫化氢（H₂S）暴露患者与202名未暴露受试者进行比较。该1997年至2001年的病例对照系列与之前16例（1991 - 1996年）病例对照患者进行比较。
方法
新患者为H₂S暴露的旁观者，均未出现昏迷。相比之下，先前组的13名成员是工作中暴露，7人曾昏迷。根据8项生理和12项心理测量指标对三组进行比较。在对年龄、性别、教育程度（年）和其他显著因素进行调整后，将观察到的测量值与预测值进行比较（观察值/预测值×100）。
结果
与未暴露对照组相比，新组表现较差，在平衡、反应时间、颜色辨别、视觉表现、听力、文化公平性、数字符号、词汇、言语回忆、钉板放置、连线测验A和B以及信息方面与第一组相似。
结论
19名工人（44%曾昏迷）和16名未昏迷的旁观者中与H₂S相关的损伤相似。
Zotero 插件