Jeganathan S, Lin C C
Department of Restorative Dentistry, National University of Singapore.
Aust Dent J. 1992 Apr;37(2):107-14. doi: 10.1111/j.1834-7819.1992.tb03046.x.
Denture stomatitis is a common recurring problem of the denture wearers. The aetiology of the disease includes infection, trauma and probably a defect in the host defence mechanism. Current thinking suggests an interplay of most of these factors in the pathogenesis of the disease. The extent of interplay of these factors is still a controversy. Candida albicans has been implicated as the causative organism. However, in the light of recent research it is debatable if it is the only causative organism. Recently, cases resistant to antifungal therapy have been reported. In such cases other micro-organisms have been isolated. At the moment, comprehensive management includes meticulous denture hygiene together with anti-fungal or antibacterial therapy and correction of denture faults.
义齿性口炎是义齿佩戴者常见的复发性问题。该病的病因包括感染、创伤，可能还有宿主防御机制缺陷。目前的观点认为，这些因素中的大多数在疾病发病机制中相互作用。这些因素相互作用的程度仍存在争议。白色念珠菌被认为是致病微生物。然而，根据最近的研究，它是否是唯一的致病微生物仍有争议。最近，有对抗真菌治疗耐药的病例报道。在这些病例中分离出了其他微生物。目前，综合治疗包括细致的义齿卫生护理以及抗真菌或抗菌治疗，同时纠正义齿缺陷。
