De Caterina Raffaele, Madonna Rosalinda, Zucchi Riccardo, La Rovere Maria Teresa
University Cardiology Division, G. d'Annunzio University, Chieti, Italy.
Am Heart J. 2003 Sep;146(3):420-30. doi: 10.1016/S0002-8703(03)00327-2.
Omega-3 polyunsaturated fatty acids are emerging as a safe and effective means to reduce sudden death after acute myocardial infarction. This review summarizes the epidemiological background for the use of omega-3 fatty acids with this indication, clinical trials performed so far, and experimental data supporting their antiarrhythmic efficacy.
ω-3多不饱和脂肪酸正逐渐成为降低急性心肌梗死后猝死的一种安全有效的方法。本综述总结了使用ω-3脂肪酸治疗该适应症的流行病学背景、迄今为止进行的临床试验以及支持其抗心律失常疗效的实验数据。