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一名11岁男孩患抗磷脂综合征,表现为扩张型心肌病。

Antiphospholipid syndrome presenting as dilated cardiomyopathy in an 11-year-old boy.

作者信息

Al-Kiyumi Wafaa A S, Venugopalan Poothirikovil

机构信息

Department of Child Health, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.

出版信息

Acta Cardiol. 2003 Aug;58(4):359-61. doi: 10.2143/AC.58.4.2005295.

Abstract

We report on an 11-year-old Omani boy who presented with acute heart failure due to dilated cardiomyopathy. Examination revealed the presence of left ventricular thrombi on echocardiography and a marked elevation of anticardiolipin antibodies. Subsequently the boy exhibited features of antiphospholipid syndrome including multiple thrombotic episodes involving the brain, and renal and iliac veins. We could not document any underlying cause of the antiphospholipid syndrome. His cardiac status subsequently deteriorated and he expired from multiorgan failure. Resistant heart failure from dilated cardiomyopathy secondary to primary antiphospholipid syndrome is uncommon and has not been reported in children.

摘要

我们报告了一名11岁的阿曼男孩,他因扩张型心肌病出现急性心力衰竭。检查发现超声心动图显示左心室有血栓,抗心磷脂抗体显著升高。随后,该男孩出现了抗磷脂综合征的特征,包括涉及脑部、肾静脉和髂静脉的多次血栓形成发作。我们未能证实抗磷脂综合征有任何潜在病因。他的心脏状况随后恶化,最终死于多器官衰竭。原发性抗磷脂综合征继发扩张型心肌病导致的难治性心力衰竭并不常见,儿童中尚未有报道。

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