Agladze Konstantin, Jackson Debra, Romeo Tony
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
J Bacteriol. 2003 Sep;185(18):5632-8. doi: 10.1128/JB.185.18.5632-5638.2003.
The complex architecture of bacterial biofilms inevitably raises the question of their design. Microstructure of developing Escherichia coli biofilms was analyzed under static and laminar flow conditions. Cell attachment during early biofilm formation exhibited periodic density patterns that persisted during development. Several models for the origination of biofilm microstructure are considered, including an activator-inhibitor or Turing model.
细菌生物膜的复杂结构不可避免地引发了其设计问题。在静态和层流条件下分析了正在形成的大肠杆菌生物膜的微观结构。早期生物膜形成过程中的细胞附着呈现出周期性密度模式，该模式在发育过程中持续存在。考虑了生物膜微观结构起源的几种模型，包括激活剂-抑制剂或图灵模型。
