Auinger Peggy, Lanphear Bruce P, Kalkwarf Heidi J, Mansour Mona E
Department of Pediatrics, University of Rochester School of Medicine and Dentistry and the American Academy of Pediatrics Center for Child Health Research, Rochester, New York 14620, USA.
Pediatrics. 2003 Sep;112(3 Pt 1):514-20. doi: 10.1542/peds.112.3.514.
The prevalence of repeated otitis media (OM) increased during the 1980s, but it is unknown if the increase has continued.
To determine trends in the prevalence of OM, early-onset OM, and repeated OM among US children from 1988 to 1994 and to identify factors that may explain any observed changes.
The Third National Health and Nutrition Examination Survey was administered in 2 phases: phase I (1988-1991) and phase II (1991-1994), each comprising a national probability sample. OM (ever having had OM), early-onset OM (first episode at <12 months of age), and repeated OM (>or=3 episodes) were assessed for 8261 children <6 years of age.
After controlling for risk factors for OM, the prevalence of OM from phase I to phase II increased from 66.7% to 69.7% (odds ratio [OR] = 1.1; 95% confidence interval [CI] =.99, 1.1), early-onset OM increased from 41.1% to 45.8% (OR = 1.1; 95% CI = 1.03, 1.2), and repeated OM increased from 34.8% to 41.1% (OR = 1.2; 95% CI = 1.1, 1.4). This observed increase corresponds to 561,000 and 720,000 more children having early-onset OM and repeated OM, respectively. Child care use, early breastfeeding termination, asthma, and access to health care did not significantly increase from phase I to phase II. The prevalence of early-onset OM and repeated OM was higher for affluent children, but the greatest increase in prevalence was among impoverished children. There was an increase in allergic conditions from phase I to phase II for poor children (22.6% to 30.2%).
The prevalence of early-onset OM and repeated OM continued to increase among preschool children in the United States. Further research to investigate this increasing prevalence should explore changes in management practice and an increase in prevalence of allergic conditions among poor children.
20世纪80年代复发性中耳炎(OM)的患病率有所上升,但这种上升趋势是否持续尚不清楚。
确定1988年至1994年美国儿童中耳炎、早发性中耳炎和复发性中耳炎患病率的趋势,并确定可能解释所观察到变化的因素。
第三次全国健康与营养检查调查分两个阶段进行:第一阶段(1988 - 1991年)和第二阶段(1991 - 1994年),每个阶段均为全国概率样本。对8261名6岁以下儿童进行了中耳炎(曾患中耳炎)、早发性中耳炎(12个月龄前首次发病)和复发性中耳炎(≥3次发作)的评估。
在控制了中耳炎的危险因素后,从第一阶段到第二阶段,中耳炎的患病率从66.7%上升到69.7%(优势比[OR]=1.1;95%置信区间[CI]=0.99, 1.1),早发性中耳炎从41.1%上升到45.8%(OR = 1.1;95% CI = 1.03, 1.2),复发性中耳炎从34.8%上升到41.1%(OR = 1.2;95% CI = 1.1, 1.4)。这一观察到的上升分别对应着多561,000名和720,000名患有早发性中耳炎和复发性中耳炎的儿童。从第一阶段到第二阶段,儿童保育的使用、早期母乳喂养的终止、哮喘以及获得医疗保健的情况均未显著增加。富裕儿童的早发性中耳炎和复发性中耳炎患病率较高,但患病率增加最多的是贫困儿童。贫困儿童从第一阶段到第二阶段过敏疾病的患病率有所上升(从22.6%升至30.2%)。
美国学龄前儿童早发性中耳炎和复发性中耳炎的患病率持续上升。进一步研究这一上升患病率应探索管理实践的变化以及贫困儿童过敏疾病患病率的增加。