Kanwar A J, Dogra S, Handa S, Parsad D, Radotra B D
Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Clin Exp Dermatol. 2003 Sep;28(5):481-5. doi: 10.1046/j.1365-2230.2003.01367.x.
Lichen planus pigmentosus is a fairly common disorder of pigmentation in Indians, but reports comprising a sizeable number of patients are lacking in the literature. We now describe the clinical and epidemiological features and histopathological findings for 124 lichen planus pigmentosus patients. A retrospective analysis of medical records of patients attending our centre during the past 12 years was undertaken. Of the 124 patients (56 male, 68 female), the majority (48.4%) had the disease for 6 months to 3 years. The face and neck were the commonest sites affected with pigmentation varying from slate grey to brownish-black. The pattern of pigmentation was mostly diffuse (77.4%), followed by reticular (9.7%), blotchy (7.3%) and perifollicular (5.6%). Lichen planus was noted in 19 patients with typical histopathological changes of the disorder. Lichen planus pigmentosus, a distinct clinical entity commonly encountered in the Indian population, should be considered in the spectrum of lichenoid disorders as a variant of lichen planus.
色素性扁平苔藓在印度人当中是一种相当常见的色素沉着性疾病,但文献中缺乏包含大量患者的报告。我们现在描述124例色素性扁平苔藓患者的临床、流行病学特征及组织病理学发现。我们对过去12年在我们中心就诊患者的病历进行了回顾性分析。在这124例患者中(56例男性,68例女性),大多数(48.4%)患病6个月至3年。面部和颈部是最常受色素沉着影响的部位,色素沉着从石板灰色到棕黑色不等。色素沉着模式大多为弥漫性(77.4%),其次是网状(9.7%)、斑点状(7.3%)和毛囊周围(5.6%)。19例患者出现扁平苔藓,具有该疾病典型的组织病理学变化。色素性扁平苔藓是印度人群中常见的一种独特临床实体,在苔藓样疾病谱中应被视为扁平苔藓的一种变体。