Madan Sanjeev, Boeree Nicholas R
Department of Orthopaedics, Wessex Deanery, Wessex, UK.
Eur Spine J. 2003 Aug;12(4):361-8. doi: 10.1007/s00586-002-0488-5. Epub 2003 Feb 27.
The objective of our study was to assess the efficacy of Graf ligamentoplasty in comparison with rigid fixation and fusion with the Hartshill horseshoe cage for similar severity of disc degeneration. Although studies have been done on the Graf ligamentoplasty procedure and the Hartshill horseshoe cage, their efficacy has never been compared in any study. This study was done to decide whether retaining mobility and stabilizing the spine is best or stiffening the lumbar segment by fusion is preferable. Between 1995 and 1997, a prospective randomized study was performed comparing Graf ligament stabilization and anterior lumbar interbody fusion. Twenty-eight patients had single-level Graf ligaments inserted and 27 patients had single-level anterior lumbar interbody fusion (ALIF) with a Hartshill horseshoe cage and tricortical iliac crest autograft. The two groups were similar in age, sex, symptoms, severity of the disc degeneration, and duration of follow-up. The chi-square test and t-test were used to evaluate the outcome. At a minimum follow-up of 2.1 years, we found that 93% of patients who had undergone Graf ligamentoplasty had a satisfactory outcome (rated "excellent" or "better") compared to 77.8% of patients who had been treated with ALIF with Hartshill horseshoe cage stabilization and fusion, when measured on the Oswestry Disability Index ( P<0.05). Retaining mobility in the lumbar segments gives better results after stabilisation with Graf ligaments than rigid fixation and fusion with the Hartshill horseshoe cage in the short term. We will be watching this cohort of patients over the next few years.
我们研究的目的是评估格拉夫韧带成形术与使用哈特希尔马蹄形椎间融合器进行刚性固定和融合治疗相似严重程度椎间盘退变的疗效。尽管已经对格拉夫韧带成形术和哈特希尔马蹄形椎间融合器进行了研究,但在任何研究中都从未对它们的疗效进行过比较。本研究旨在确定保留脊柱活动度并使其稳定是否最佳,还是通过融合使腰椎节段僵硬更可取。在1995年至1997年期间,进行了一项前瞻性随机研究,比较格拉夫韧带稳定术和腰椎前路椎间融合术。28例患者植入了单节段格拉夫韧带,27例患者接受了单节段腰椎前路椎间融合术(ALIF),使用哈特希尔马蹄形椎间融合器并取自体三面皮质髂嵴骨移植。两组在年龄、性别、症状、椎间盘退变严重程度和随访时间方面相似。采用卡方检验和t检验评估结果。在至少2.1年的随访中,我们发现,根据奥斯威斯利功能障碍指数测量,接受格拉夫韧带成形术的患者中有93%获得了满意的结果(评为“优秀”或“较好”),而接受哈特希尔马蹄形椎间融合器稳定和融合的ALIF治疗的患者中这一比例为77.8%(P<0.05)。在短期内,与使用哈特希尔马蹄形椎间融合器进行刚性固定和融合相比,使用格拉夫韧带稳定腰椎节段并保留其活动度能带来更好的结果。我们将在未来几年对这组患者进行观察。