脆弱拟杆菌血液及其他肠外样本分离株中脆弱溶素基因的流行情况。
Prevalence of fragilysin gene in Bacteroides fragilis isolates from blood and other extraintestinal samples.
作者信息
Foulon Ina, Piérard Denis, Muyldermans Gaëtan, Vandoorslaer Kristof, Soetens Oriane, Rosseel Paul, Lauwers Sabine
机构信息
Department of Microbiology, Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium.
出版信息
J Clin Microbiol. 2003 Sep;41(9):4428-30. doi: 10.1128/JCM.41.9.4428-4430.2003.
Abstract
Of 166 Bacteroides fragilis isolates, 26.2% of 103 isolates from blood and 20.6% of 63 extraintestinal isolates harbored the fragilysin gene (difference not statistically significant). Clinical characteristics and evolution were comparable in patients with B. fragilis bacteremia with or without this enterotoxin. Fragilysin seems not to be an important virulence factor in B. fragilis disease.
摘要
在166株脆弱拟杆菌分离株中，来自血液的103株分离株中有26.2%以及63株肠外分离株中有20.6%携带脆弱溶血素基因（差异无统计学意义）。有或无这种肠毒素的脆弱拟杆菌菌血症患者的临床特征和病程相似。脆弱溶血素似乎不是脆弱拟杆菌疾病中的重要毒力因子。
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