Branger S, Casalta J P, Habib G, Collard F, Raoult D
Laboratoire de Microbiologie, Centre Hospitalier Universitaire La Timone, Marseille, France.
J Clin Microbiol. 2003 Sep;41(9):4435-7. doi: 10.1128/JCM.41.9.4435-4437.2003.
We amplified by PCR and sequenced Streptococcus pneumoniae rpoB from DNA of the cardiac valve of a man who had presented with pneumococcal endocarditis 7 years earlier. Histopathologically, the valve did not show evidence of endocarditis. This case raises the question of persistence of DNA without any evidence of infection.
我们通过聚合酶链反应(PCR)扩增并测序了一名7年前患有肺炎球菌性心内膜炎男性心脏瓣膜DNA中的肺炎链球菌rpoB基因。组织病理学检查显示,该瓣膜未发现心内膜炎迹象。此病例提出了在无任何感染证据情况下DNA持续存在的问题。