Buchanan Claire L, Sullivan Vita V, Lampman Richard, Kulkarni Mohan G
Department of Surgery, St. Joseph Mercy Hospital, Ann Arbor, Michigan 48106, USA.
Ann Thorac Surg. 2003 Sep;76(3):817-20. doi: 10.1016/s0003-4975(03)00666-0.
The most effective method for managing pericardial effusions has yet to be identified. This study evaluates the efficacy and safety of echocardiographic-guided placement of indwelling catheters into the pericardial space.
This study consists of a 5-year retrospective chart review of consecutive patients coded with benign or malignant pericardial effusions who presented for drainage procedures to a single surgeon at a 260-bed hospital. Complication, recurrence, and survival rates were studied.
Between January 1996 and August 2001, a total of 29 pericardial drainage procedures were performed; eight of those also underwent talc sclerosis. Mean follow-up was 16 months. Three patients (10%) required conversion to thoracotomy; of those remaining, 25 of the 26 procedures were performed under local anesthesia with intravenous sedation. The identified etiologies for pericardial effusions were malignancy (76%), idiopathic (14%), postcoronary artery bypass grafting procedure (3%), viral pericarditis (3%), and uremia (3%). Echocardiographic features of tamponade were documented in 72%. Mean +/- SEM length of postprocedure in-hospital stay was 6.7 +/- 0.82 days. The overall complication rate was 10% (pneumothorax and cardiac injury). Recurrence rate within 30 days was 7%. Thirty-day mortality was 21%, and more than 90-day survival was 72%.
Pericardiocentesis with extended catheter drainage is a safe treatment for management of clinically significant, malignant and benign, pericardial effusions and can be performed effectively under local anesthesia with intravenous sedation.
目前尚未确定处理心包积液的最有效方法。本研究评估了超声心动图引导下将留置导管置入心包腔的有效性和安全性。
本研究包括对一家拥有260张床位的医院中,由同一位外科医生进行引流手术的连续编码为良性或恶性心包积液患者的5年回顾性病历审查。研究了并发症、复发率和生存率。
1996年1月至2001年8月,共进行了29例心包引流手术;其中8例还接受了滑石粉硬化治疗。平均随访时间为16个月。3例患者(10%)需要转为开胸手术;其余患者中,26例手术中有25例在局部麻醉加静脉镇静下进行。心包积液的确定病因包括恶性肿瘤(76%)、特发性(14%)、冠状动脉搭桥术后(3%)、病毒性心包炎(3%)和尿毒症(3%)。72%记录了心包填塞的超声心动图特征。术后平均住院时间为6.7±0.82天。总体并发症发生率为10%(气胸和心脏损伤)。30天内的复发率为7%。30天死亡率为21%,90天以上生存率为72%。
心包穿刺置管引流是治疗临床上有意义的恶性和良性心包积液的安全方法,可在局部麻醉加静脉镇静下有效进行。