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金黄色葡萄球菌的脂磷壁酸和肽聚糖协同诱导中性粒细胞流入小鼠肺部。

Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice.

作者信息

Leemans Jaklien C, Heikens Mirjam, van Kessel Kok P M, Florquin Sandrine, van der Poll Tom

机构信息

Laboratory of Experimental Internal Medicine, Utrecht University, Utrecht, The Netherlands.

出版信息

Clin Diagn Lab Immunol. 2003 Sep;10(5):950-3. doi: 10.1128/cdli.10.5.950-953.2003.

Abstract

Staphylococcus aureus is an important pathogen in nosocomial pneumonia. Lipoteichoic acid (LTA) and peptidoglycan (PepG) are part of the staphylococcal cell wall. Here we show that LTA and PepG act in synergy to cause polymorphonuclear cell recruitment in the pulmonary compartment during S. aureus pneumonia.

摘要

金黄色葡萄球菌是医院获得性肺炎中的一种重要病原体。脂磷壁酸(LTA)和肽聚糖(PepG)是葡萄球菌细胞壁的组成部分。在此我们表明,在金黄色葡萄球菌肺炎期间,LTA和PepG协同作用导致肺组织中多形核细胞募集。

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