金黄色葡萄球菌的脂磷壁酸和肽聚糖协同诱导中性粒细胞流入小鼠肺部。
Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice.
作者信息
Leemans Jaklien C, Heikens Mirjam, van Kessel Kok P M, Florquin Sandrine, van der Poll Tom
机构信息
Laboratory of Experimental Internal Medicine, Utrecht University, Utrecht, The Netherlands.
出版信息
Clin Diagn Lab Immunol. 2003 Sep;10(5):950-3. doi: 10.1128/cdli.10.5.950-953.2003.
Abstract
Staphylococcus aureus is an important pathogen in nosocomial pneumonia. Lipoteichoic acid (LTA) and peptidoglycan (PepG) are part of the staphylococcal cell wall. Here we show that LTA and PepG act in synergy to cause polymorphonuclear cell recruitment in the pulmonary compartment during S. aureus pneumonia.
摘要
金黄色葡萄球菌是医院获得性肺炎中的一种重要病原体。脂磷壁酸（LTA）和肽聚糖（PepG）是葡萄球菌细胞壁的组成部分。在此我们表明，在金黄色葡萄球菌肺炎期间，LTA和PepG协同作用导致肺组织中多形核细胞募集。
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本文引用的文献
1
CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats.CXC趋化因子KC和巨噬细胞炎性蛋白-2（MIP-2）协同诱导白细胞向大鼠中枢神经系统募集。
Immunol Lett. 2003 Jan 2;85(1):1-4. doi: 10.1016/s0165-2478(02)00200-6.
2
Differential role of interleukin-6 in lung inflammation induced by lipoteichoic acid and peptidoglycan from Staphylococcus aureus.白细胞介素-6在金黄色葡萄球菌脂磷壁酸和肽聚糖诱导的肺部炎症中的不同作用。
Am J Respir Crit Care Med. 2002 May 15;165(10):1445-50. doi: 10.1164/rccm.2106045.
3
Synergy between TLR2 and TLR4: a safety mechanism.Toll样受体2与Toll样受体4之间的协同作用：一种安全机制。
Blood Cells Mol Dis. 2001 Jul-Aug;27(4):728-30. doi: 10.1006/bcmd.2001.0441.
4
Toll-like receptors; their physiological role and signal transduction system.Toll样受体；它们的生理作用和信号转导系统。
Int Immunopharmacol. 2001 Apr;1(4):625-35. doi: 10.1016/s1567-5769(01)00010-8.
5
Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8.微球菌和肽聚糖激活TLR2→MyD88→IRAK→TRAF→NIK→IKK→NF-κB信号转导通路，该通路可诱导白细胞介素-8的转录。
Infect Immun. 2001 Apr;69(4):2270-6. doi: 10.1128/IAI.69.4.2270-2276.2001.
6
A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the rat.来自致病性和非致病性革兰氏阳性菌的一种细胞壁成分（肽聚糖）与内毒素协同作用，导致大鼠体内肿瘤坏死因子-α释放、一氧化氮生成、休克以及多器官损伤/功能障碍。
Shock. 2001 Feb;15(2):135-42. doi: 10.1097/00024382-200115020-00010.
7
MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components.髓样分化蛋白2（MD-2）可使Toll样受体2（TLR2）介导对脂多糖的反应，并增强TLR2介导对革兰氏阳性菌和革兰氏阴性菌及其细胞壁成分的反应。
J Immunol. 2001 Feb 1;166(3):1938-44. doi: 10.4049/jimmunol.166.3.1938.
8
A Toll-like receptor recognizes bacterial DNA.一种Toll样受体可识别细菌DNA。
Nature. 2000 Dec 7;408(6813):740-5. doi: 10.1038/35047123.
9
Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways.Toll样受体（TLR）2和TLR4介导的信号通路之间的协同作用和交叉耐受性。
J Immunol. 2000 Dec 15;165(12):7096-101. doi: 10.4049/jimmunol.165.12.7096.
10
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Am J Respir Crit Care Med. 2000 Aug;162(2 Pt 1):486-9. doi: 10.1164/ajrccm.162.2.9911009.
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