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一例伴有致命结局的严重急性呼吸综合征的影像学特征

Radiographic features of a case of severe acute respiratory syndrome with fatal outcome.

作者信息

Tan D Y, Kaw G J, Tsou I Y, Wansaicheong G K, Green J A, Tai D Y, Chee T S

机构信息

Department of Diagnostic Radiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.

出版信息

Ann Acad Med Singap. 2003 Jul;32(4):542-6.

Abstract

INTRODUCTION

Severe acute respiratory syndrome (SARS) is a new form of atypical pneumonia caused by a coronavirus. We present the clinical course and chest radiographic findings of a case of SARS with fatal outcome.

CLINICAL PICTURE

A 39-year-old Chinese male presented with fever, sore throat and non-productive cough. During his illness, serial chest radiographs showed increasingly severe air-space shadowing in both lungs.

TREATMENT AND OUTCOME

The patient was treated with supplemental oxygen, levofloxacin, oseltamivir, ribavirin and methylprednisolone. As his condition worsened, the required ventilatory and inotropic support. He later developed a myocardial infarct and coagulopathy, and succumbed to his illness.

CONCLUSION

The reported case mortality of SARS is about 9% worldwide. In Singapore, the mortality is 15.5%. Acute respiratory distress syndrome (ARDS) is believed to be a contributory factor to our patient's demise. We report this case to show the radiographic changes of ARDS in a patient with SARS.

摘要

引言

严重急性呼吸综合征(SARS)是一种由冠状病毒引起的新型非典型肺炎。我们报告一例SARS致死病例的临床病程及胸部X线表现。

临床表现

一名39岁中国男性,表现为发热、咽痛及干咳。患病期间,系列胸部X线片显示双肺气腔阴影逐渐加重。

治疗及转归

患者接受了吸氧、左氧氟沙星、奥司他韦、利巴韦林及甲泼尼龙治疗。随着病情恶化,需要通气及强心支持。他后来发生心肌梗死及凝血病,并最终病故。

结论

全球报告的SARS病例死亡率约为9%。在新加坡,死亡率为15.5%。急性呼吸窘迫综合征(ARDS)被认为是导致我们这位患者死亡的一个因素。我们报告此病例以展示SARS患者中ARDS的影像学变化。

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