Holley Jean L, Reddy Sai Subhodhini
Semin Dial. 2003 Sep-Oct;16(5):384-8. doi: 10.1046/j.1525-139x.2003.16085.x.
Although uncommon, pregnancy occurs in women on chronic dialysis. In 1980 the incidence of pregnancy in women on dialysis was 0.9%. Studies from 1992 to 2003 indicate that pregnancy occurred in 1-7% of women on chronic dialysis. Half of the infants born to women on chronic dialysis survive. Of importance is that "intensive dialysis" of 16-24 hr/week is associated with improved infant survival. In this article, the incidence, duration, fetal and maternal complications, and outcomes of pregnancy in women on chronic dialysis are reviewed. The management of anemia, hypertension, electrolytes, bone minerals, and acid-base parameters in the pregnant dialysis patient is also summarized. Recommendations regarding the dialysis prescription for the pregnant woman on hemodialysis (HD) or peritoneal dialysis (PD) are also made. The complex and precarious condition of the pregnant woman on dialysis requires close collaboration between the patient, nephrologist, dialysis staff, obstetrician, and neonatologist to maximize the chance of a successful pregnancy.
尽管并不常见，但慢性透析患者中仍会发生妊娠。1980年，透析女性的妊娠发生率为0.9%。1992年至2003年的研究表明，慢性透析女性中1% - 7%会发生妊娠。慢性透析女性所生婴儿中有一半存活。重要的是，每周进行16 - 24小时的“强化透析”与婴儿存活率提高有关。本文回顾了慢性透析女性的妊娠发生率、持续时间、胎儿和母亲并发症及妊娠结局。还总结了妊娠透析患者贫血、高血压、电解质、骨矿物质和酸碱参数的管理。此外，还针对接受血液透析（HD）或腹膜透析（PD）的妊娠女性的透析处方提出了建议。透析妊娠女性的情况复杂且不稳定，需要患者、肾病科医生、透析工作人员、产科医生和新生儿科医生密切合作，以最大限度地提高妊娠成功的几率。
