Pawlik B, Bogusz B
Zakład Mykologii Instytutu Mikrobiologii AM, Krakowie.
Med Dosw Mikrobiol. 1992;44(1-2):75-82.
Frequency of appearance of Candida krusei in human reproductive tract, susceptibility of these microorganisms to drugs and their importance in pathogenesis of mycosis, were investigated. Strains C. krusei species constituted 6.7% of the total 1325 strains and 21.8% within other than C. albicans species yeast-like fungi. Vaginal mycosis caused by fungi from C. krusei species occurs in presence of Lactobacillus sp. and correct values of pH in vaginal contents, however changed leukocytosis in evident. Over 60% of patients with C. krusei infection were complaining that they feel disturbances within the reproductive tract. Investigation of susceptibility of C. krusei to drugs revealed highest activity of cotrimazine and pimaricin.
研究了克鲁斯念珠菌在人类生殖道中的出现频率、这些微生物对药物的敏感性及其在真菌病发病机制中的重要性。克鲁斯念珠菌菌株占1325株总菌株的6.7%,在白色念珠菌以外的其他酵母样真菌中占21.8%。克鲁斯念珠菌属真菌引起的阴道真菌病发生在存在乳酸杆菌且阴道内容物pH值正常的情况下,然而明显的白细胞增多现象发生了变化。超过60%的克鲁斯念珠菌感染患者抱怨他们感到生殖道内有不适。对克鲁斯念珠菌对药物的敏感性研究表明,复方磺胺甲恶唑和匹马霉素的活性最高。