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[克非尔假丝酵母(类热带假丝酵母)在生殖道感染中的作用]

[The role of Candida kefyr (C. pseudotropicalis) in reproductive tract infections].

作者信息

Pawlik B, Jodłowska V

机构信息

Zakład Mykologii Instytutu Mikrobiologii AM, Krakowie.

出版信息

Med Dosw Mikrobiol. 1992;44(1-2):83-8.

PMID:1297040
Abstract

Frequency of appearance of C. kefyr strains, their diagnosis, susceptibility to drugs and importance in pathogenesis of reproductive tract mycoses were investigated. The investigated material consisted of 2717 strains, and there were 67 strains of C. kefyr isolated from vaginal mucous membrane. C. kefyr strains constituted 2.5% of total number of 2717 isolated strains and 8.2% within fungi other than C. albicans species. Vaginal mycosis caused by C. kefyr occurs in presence of Lactobacillus sp. and correct values of pH in vaginal contents, however changing leukocyte number was observed. Clinical symptoms and complaints regarding reproductive tract were present in 47.8% of patients with C. kefyr infections. Investigating susceptibility to antimycotic drugs, regardless of appointed method, low susceptibility of C. kefyr strains to amphotericin B was noted (79% resistant strains). Strain of C. kefyr were sensitive to all remaining drugs.

摘要

对克菲酵母菌株的出现频率、诊断、药物敏感性及其在生殖道真菌病发病机制中的重要性进行了研究。研究材料包括2717株菌株,其中从阴道黏膜分离出67株克菲酵母菌株。克菲酵母菌株占2717株分离菌株总数的2.5%,在白色念珠菌属以外的真菌中占8.2%。由克菲酵母引起的阴道真菌病发生在存在乳酸杆菌属且阴道内容物pH值正常的情况下,但观察到白细胞数量发生变化。47.8%的克菲酵母感染患者出现了关于生殖道的临床症状和主诉。在研究抗真菌药物敏感性时,无论采用何种指定方法,均发现克菲酵母菌株对两性霉素B的敏感性较低(79%为耐药菌株)。克菲酵母菌株对所有其余药物敏感。

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