Balakshina V V, Kulakov L A, Boronin A M
Mikrobiologiia. 1992 Nov-Dec;61(6):1051-5.
The population interactions of Pseudomonas aeruginosa virulent bacteriophage phi mF81 with host bacterial cells were studied in dynamics under the conditions of continuous cultivation in the chemostat regime with glucose limitation. It was detected that a maintenance of the bacterium and its specific bacteriophage in the population was realized due to the successive appearance of bacterial mutants resistant to the phage and of phage mutants overcoming this resistance.
在葡萄糖受限的恒化器连续培养条件下,对铜绿假单胞菌烈性噬菌体φmF81与宿主细菌细胞的群体相互作用进行了动态研究。结果发现,由于对噬菌体具有抗性的细菌突变体和克服这种抗性的噬菌体突变体相继出现,该细菌及其特异性噬菌体在群体中得以维持。