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[铝工业中肿瘤的预防]

[The prevention of tumors in the aluminum industry].

作者信息

Clonfero E, Ballarin C

机构信息

Istituto di Medicina del Lavoro, Università di Padova.

出版信息

Med Lav. 1992 Sep-Oct;83(5):499-505.

PMID:1297064
Abstract

Aluminium industry workers are exposed to various carcinogenic substances, the most important of which are asbestos and coal pitch and tar fumes. Primary prevention of cancer risk can be achieved either by eliminating the carcinogenic agent from the working environment, or by reducing the exposure levels or the number of exposed workers. In the aluminium industry the first type of approach is possible in the case of asbestos, which can be substituted with MMMF (man made mineral fibers), with the cancer risk thus passing from group 1 to group 2b of the IARC Classification. Complete abolition of exposure to pitch and coal-tar fumes is not feasible, but a reduction in risk can be achieved by using the pre-bake anode cell process instead of the Söderberg process, since the former reduces exposure of potroom workers to pitch and coal-tar fumes. A further reduction of exposure in pot-rooms can be achieved, as demonstrated by direct experience in an aluminium plant at Port Marghera (Province of Venice). Environmental monitoring performed from 1978 to 1989 showed a decrease in levels of total dust concentrations and thus of PAH and BaP concentrations as a result of a series of technical and/or organisational improvements. In biological monitoring, which can detect any skin absorption of the carcinogen, the concentrations of urinary hydroxypyrene confirmed low levels of exposure in the plant under study, excluding the pitch plant workers.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

铝工业工人会接触到各种致癌物质,其中最重要的是石棉、煤沥青和焦油烟雾。癌症风险的一级预防可以通过从工作环境中消除致癌剂,或通过降低接触水平或减少接触工人的数量来实现。在铝工业中,对于石棉来说,第一种方法是可行的,石棉可以用MMMF(人造矿物纤维)替代,这样癌症风险就从国际癌症研究机构分类的第1组变为第2B组。完全消除对焦油和煤焦油烟雾的接触是不可行的,但可以通过使用预焙阳极电解槽工艺而不是索德伯格工艺来降低风险,因为前者减少了电解车间工人对焦油和煤焦油烟雾的接触。正如威尼斯省马尔盖拉港一家铝厂的直接经验所示,电解车间的接触还可以进一步降低。1978年至1989年进行的环境监测表明,由于一系列技术和/或组织改进,总粉尘浓度以及多环芳烃和苯并[a]芘浓度有所下降。在能够检测致癌物任何皮肤吸收情况的生物监测中,尿中羟基芘的浓度证实了所研究工厂的接触水平较低,但沥青厂工人除外。(摘要截于250字)

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