Snoeck J, Decoster H, Marchand X, Kahn J C, Baron B, Zannier D, Pathé M, Verherstraeten M, Vrints C, Heuten H
Département de cardiologie, hôpital universitaire d'Anvers, Edegem, Belgique.
Arch Mal Coeur Vaiss. 1992 Oct;85(10):1419-24.
The P waves of patients with VVI pacemakers were compared with those of DDD pacemakers at implantation and then regularly for 5 years. A certain number of cardiac pathologies are known to cause P wave changes. The incidence of atrial fibrillation (AF) was much higher in VVI than in DDD patients. In the VVI group, the incidence was much greater in patients paced for sinus node disease than in patients paced for AVB. Analysis of sinus P wave characteristics in 320 patients with VVI pacemakers shows progressive abnormalities of atrial function with time. The expression of this atrial dysfunction is a statistically significant prolongation of the P wave in V1 and dII and of the terminal part of the P wave in V1. The factors responsible for this abnormality and which favours the occurrence of AF are quasi-permanent pacing, the presence of retrograde conduction and an abnormality of atrial activation at the time of implantation.
对植入VVI起搏器的患者与植入DDD起搏器的患者在植入时及之后5年进行定期的P波比较。已知一定数量的心脏病变会导致P波改变。VVI起搏器患者的心房颤动（AF）发生率远高于DDD起搏器患者。在VVI组中，因窦房结疾病而接受起搏治疗的患者的发生率远高于因房室传导阻滞而接受起搏治疗的患者。对320例VVI起搏器患者的窦性P波特征分析显示，心房功能随时间逐渐出现异常。这种心房功能障碍的表现为V1和dII导联P波以及V1导联P波终末部分在统计学上显著延长。导致这种异常并促进房颤发生的因素包括长期起搏、存在逆向传导以及植入时心房激动异常。
