Mitchell John D
Section of General Thoracic Surgery, University of Colorado School of Medicine, Division of Cardiothoracic Surgery, Denver, CO, USA.
Semin Thorac Cardiovasc Surg. 2003 Jul;15(3):305-9. doi: 10.1016/s1043-0679(03)70011-2.
Solitary fibrous tumors of the pleura are an uncommon but increasingly recognized neoplasm derived from mesenchymal cells located in the submesothelial lining of the pleural space. They may be differentiated from mesotheliomas and other pleural tumors due to unique immunohistochemical characteristics. The vast majority of these tumors are benign, and complete surgical resection remains the mainstay of therapy for both the benign and malignant variants. In this review, the clinical presentation, radiologic features, histologic findings, and treatment options for this tumor are described.
胸膜孤立性纤维瘤是一种罕见但越来越被认识到的肿瘤,起源于胸膜腔间皮细胞下的间充质细胞。由于其独特的免疫组化特征,它们可与间皮瘤和其他胸膜肿瘤相鉴别。这些肿瘤绝大多数是良性的,完整的手术切除仍然是良性和恶性变体治疗的主要方法。在这篇综述中,描述了这种肿瘤的临床表现、放射学特征、组织学发现和治疗选择。