Zhu Wenzhen, Qi Jianpin, Wang Chengyuan
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
J Huazhong Univ Sci Technolog Med Sci. 2003;23(2):180-3. doi: 10.1007/BF02859951.
The utility of three-dimensional spoiled gradient recalled acquisition in steady state (3D-SPGR) imaging in the cerebral diseases was evaluated and 3D-SPGR after enhancement in depicting contrast enhancement of all lesions and 2D-SE T1WI comparatively analyzed. 117 patients were subjected to MRI by a GE 1.5T MR system. After performance of axial T1WI and T2WI in all patients, MRA (3D-MOTSA) images were acquired in 6 cases (8 lesions) of aneurysms. After enhancement, 3D-SPGR images were obtained in all the remaining patients. Quality parameters (SNR, C and CNR) were calculated on enhanced 2D-SE T1WI and 3D-SPGR images. And a four-point scale was used to measure the signal intensity of the main lesions on both sequences, then statistical analysis of the average score was performed with "t" test. Except for aneurysms, 2D-SE T1WI detected 134 lesions and 3D-SPGR disclosed 147 lesions. It was found that there was no statistically significant difference between the two average scores as determined by the "t" test (t = 1,894, P > 0.05). The enhancement degree of the main lesion was equivalent on 3D-SPGR and 2D-SE T1WI. Quality parameters (SNR, C and CNR) on 2D-SE T1WI were much larger than that of 3D-SPGR, increasing by an average of 57%, 20% and 97% respectively. 3D-SPGR imaging with MPR could clearly depict vascularity related to neoplasms in 20 cases and demonstrate shifted, deformed and blocked vessels involved by tumors. Six cases of large aneurysms (8 lesions) were visualized more clearly on 3D-SPGR than MRA (3D-MOTSA): 3D-SPGR could display aneurysm necks and differentiate thrombosed portion from the patent lumen, and disclose relationship of aneurysm to surrounding structures. It was concluded that enhanced 3D-SPGR played an important role in the depiction of the cerebral lesions and was superior to 2D-SE T1WI in many aspects.
评估了三维稳态扰相梯度回波采集（3D-SPGR）成像在脑部疾病中的应用价值，并对增强后的3D-SPGR与二维自旋回波T1加权成像（2D-SE T1WI）在显示所有病变的对比增强方面进行了比较分析。117例患者接受了GE 1.5T MR系统的MRI检查。在所有患者均进行了轴位T1WI和T2WI检查后，对6例（8个病变）动脉瘤患者进行了磁共振血管造影（3D-MOTSA）成像。增强后，对其余所有患者均进行了3D-SPGR成像。在增强后的2D-SE T1WI和3D-SPGR图像上计算质量参数（信噪比、对比噪声比和对比度）。并采用四点量表测量两个序列上主要病变的信号强度，然后用“t”检验对平均分进行统计分析。除动脉瘤外，2D-SE T1WI检测到134个病变，3D-SPGR显示出147个病变。发现“t”检验确定的两个平均分之间无统计学显著差异（t = 1.894，P > 0.05）。3D-SPGR和2D-SE T1WI上主要病变的强化程度相当。2D-SE T1WI上的质量参数（信噪比、对比噪声比和对比度）远大于3D-SPGR，平均分别增加了57%、20%和97%。采用多平面重组（MPR）的3D-SPGR成像能够清晰显示20例肿瘤相关血管，并显示肿瘤累及的移位、变形和阻塞血管。6例大动脉瘤（8个病变）在3D-SPGR上比磁共振血管造影（3D-MOTSA）显示得更清晰：3D-SPGR能够显示动脉瘤颈，区分血栓形成部分与通畅管腔，并揭示动脉瘤与周围结构的关系。得出结论，增强后的3D-SPGR在脑部病变的显示中发挥了重要作用，在许多方面优于2D-SE T1WI。
