Mirowitz S A
Department of Radiology, Jewish Hospital at Washington University Medical Center, Washington University School of Medicine, St Louis, MO 63110.
Radiology. 1992 Nov;185(2):529-34. doi: 10.1148/radiology.185.2.1410367.
The conspicuity of lesion enhancement with gadopentetate dimeglumine was evaluated subjectively and quantitatively through calculation of contrast-to-noise ratios (C/Ns) on T1-weighted three-dimensional (3D) Fourier transform (FT) gradient-echo (GRE) and two-dimensional (2D) FT spin-echo (SE) images of the brain in 406 consecutive patients. One hundred one enhancing intracranial lesions were present in 61 patients, including intra-(n = 76) and extraaxial (n = 25) processes of neoplastic (n = 68), infectious or inflammatory (n = 13), ischemic (n = 11), or vascular (n = 9) origin. Enhancement was apparent in all lesions on 2DFT SE and 3DFT GRE images, with similar subjective conspicuity in 86.8% (87 of 101) of lesions. Quantitative C/N measurements for 2DFT SE (mean, 17.6) and 3DFT GRE (mean, 17.2) imaging were not significantly different (P = .72). These findings, along with the other advantages of 3DFT GRE imaging, indicate that 3DFT GRE examinations are likely to play a major role in the performance of contrast-enhanced MR imaging of the brain.
通过计算406例连续患者脑部T1加权三维（3D）傅里叶变换（FT）梯度回波（GRE）和二维（2D）FT自旋回波（SE）图像的对比噪声比（C/N），对钆喷酸葡胺增强病变的明显程度进行了主观和定量评估。61例患者中存在101个强化的颅内病变，包括肿瘤性（n = 68）、感染性或炎症性（n = 13）、缺血性（n = 11）或血管性（n = 9）起源的颅内（n = 76）和脑外（n = 25）病变。在2DFT SE和3DFT GRE图像上所有病变均有强化表现，86.8%（101个病变中的87个）的病变主观明显程度相似。2DFT SE成像（平均值为17.6）和3DFT GRE成像（平均值为17.2）的定量C/N测量结果无显著差异（P = 0.72）。这些发现以及3DFT GRE成像的其他优势表明，3DFT GRE检查可能在脑部对比增强磁共振成像中发挥主要作用。
