Stabbert R, Voncken P, Rustemeier K, Haussmann H-J, Roemer E, Schaffernicht H, Patskan G
Philip Morris Research Laboratories, Fuggerstrasse 3, D-51149 Köln, Germany.
J Appl Toxicol. 2003 Sep-Oct;23(5):329-39. doi: 10.1002/jat.924.
The chemical composition of mainstream smoke from an electrically heated cigarette (EHC) and that of mainstream smoke from the University of Kentucky Reference Cigarette 1R4F was analyzed. In contrast to the 1R4F, which is a conventional, lit-end cigarette, the EHC is smoked in a microprocessor-controlled lighter with electrical heater elements. The electrical heating causes the tobacco under the heater element to burn at a low temperature during each puff. A comprehensive list of chemical constituents was analyzed in mainstream smoke. The list is a combination of those compounds suggested for analysis in cigarette smoke by a US Consumer Product Safety Commission proposal in 1993, and those cigarette smoke constituents identified by the International Agency on Research on Cancer as being present in cigarette smoke and characterized as carcinogens. The low pyrolysis/combustion temperature of tobacco in the EHC causes distinct shifts in the composition of the smoke compared with a conventional cigarette. A significant drop was seen in the yields of almost all toxicologically relevant constituents. On a per cigarette basis almost two-thirds of the constituents were reduced by at least 80%, whereas on an equal total particulate matter basis about two-thirds of the constituents were reduced by at least 50%, with many constituents reduced by more than 90%.
对电加热卷烟（EHC）主流烟气的化学成分以及肯塔基大学参考卷烟1R4F主流烟气的化学成分进行了分析。与传统的点燃式端吸卷烟1R4F不同，EHC是在带有电加热元件的微处理器控制打火机中抽吸的。电加热使加热元件下方的烟草在每次抽吸时低温燃烧。对主流烟气中的化学成分进行了全面分析。该清单是1993年美国消费品安全委员会提案中建议分析的卷烟烟气化合物，以及国际癌症研究机构确定存在于卷烟烟气中并被定性为致癌物的那些卷烟烟气成分的组合。与传统卷烟相比，EHC中烟草的低热解/燃烧温度导致烟气成分发生明显变化。几乎所有毒理学相关成分的产率都显著下降。以每支卷烟计，近三分之二的成分减少了至少80%，而以等总颗粒物计，约三分之二的成分减少了至少50%，许多成分减少了90%以上。
