Braga P C, Allegra L, Dall'Oglio G, Angelini M, Mocchi A
Center for Respiratory Pharmacology, School of Medicine, University of Milan, Italy.
Biorheology. 1992 Mar-Jun;29(2-3):285-93. doi: 10.3233/bir-1992-292-308.
Changes in production and in physico-chemical properties of bronchial mucus is a common denominator of many pulmonary diseases. A rheometer with innovative features aimed at bronchial mucus routine investigation in clinical practice at the bedside of the patient has been designed. Searle-type configuration with a coaxial cylinder sensor system and the Mooney-Ewart geometry has been adopted. Another new feature is that bob and cup are disposable. Dynamic viscoelasticity is calculated through a microprocessor with specific software and by means of a magnetic torque--motor electronically driven by the microprocessor. The self-zeroing procedure and the autorange greatly simplify the measuring-cycle which is driven by only one switch. Data (eta and G') are automatically printed on paper. The whole measuring-cycle at the bedside of the patient takes 3-5 min, so that in 1h about 12 samples can be investigated.
支气管黏液生成及理化性质的改变是许多肺部疾病的共同特征。已设计出一种具有创新特性的流变仪,旨在用于临床实践中患者床边的支气管黏液常规检测。采用了带有同轴圆柱传感器系统和穆尼-尤尔特几何形状的 Searle 型配置。另一个新特性是圆柱和杯体为一次性使用。动态黏弹性通过带有特定软件的微处理器并借助由微处理器电子驱动的磁转矩电机进行计算。自动调零程序和自动量程极大地简化了仅由一个开关驱动的测量周期。数据(η和 G')会自动打印在纸上。在患者床边进行整个测量周期耗时 3 - 5 分钟,因此 1 小时内大约可检测 12 个样本。