Chen D, Li S
Hua Xi Yi Ke Da Xue Xue Bao. 1992 Sep;23(3):335-8.
Thirteen cases of epithelioid sarcoma were studied by light microscopy (LM), electron microscopy and immunohistochemical technique. LM revealed a nodular pattern of the tumor cells, which consisted of various degrees of a typical epithelioid cells and plump spindle-shaped cells. Irregular necrosis was seen in the centre of some nodules. Ultrastructurally the tumor cells exhibited abundant intermediate filaments, desmosome-like cell junctions and small intercellular spaces surrounded by microvilli. Immunohistochemically, there was positivity for vimentin and keratin. The author discussed diagnosis, differential diagnosis and histogenesis of epithelioid sarcoma.
通过光学显微镜(LM)、电子显微镜和免疫组织化学技术对13例上皮样肉瘤进行了研究。光学显微镜显示肿瘤细胞呈结节状模式,由不同程度的典型上皮样细胞和饱满的梭形细胞组成。在一些结节的中心可见不规则坏死。超微结构上,肿瘤细胞表现出丰富的中间丝、桥粒样细胞连接以及被微绒毛包围的小细胞间隙。免疫组织化学显示波形蛋白和角蛋白呈阳性。作者讨论了上皮样肉瘤的诊断、鉴别诊断和组织发生。