Morino P, Herrera-Marschitz M, Meana J J, Ungerstedt U, Hökfelt T
Department of Histology and Neurobiology, Karolinska Institute, Stockholm, Sweden.
Neurosci Lett. 1992 Dec 14;148(1-2):133-6. doi: 10.1016/0304-3940(92)90822-o.
Using the indirect immunofluorescence technique, the effects of decortication and callosotomy on the pattern of cholecystokinin (CCK)-like immunoreactivity were studied in the striatum of the rat. Decortication plus callosotomy, but not decortication alone, caused a strong decrease in the immunoreactivity on the side ipsilateral to the lesion. An almost complete disappearance of CCK immunoreactive patches in the medial-dorsal aspects of the striatum was observed. These results indicate that part of the striatal CCK immunoreactive fibres are of cortical origin, to a considerable extent from the contralateral side.
运用间接免疫荧光技术，研究了去皮质术和胼胝体切开术对大鼠纹状体中胆囊收缩素（CCK）样免疫反应性模式的影响。去皮质术加胼胝体切开术，而非单独的去皮质术，导致损伤同侧的免疫反应性显著降低。观察到纹状体背内侧区域CCK免疫反应性斑块几乎完全消失。这些结果表明，纹状体中部分CCK免疫反应性纤维起源于皮质，相当一部分来自对侧。
