Malinowski A, Szpakowski M, Tchórzewski H, Kowalczyk T, Podciechowski L, Zeman K, Oszukowski P
Katedry Połoznictwa i Ginekologii WAM, Lodzi.
Ginekol Pol. 1992 Sep;63(9):433-8.
T lymphocyte subpopulations (CD3+, CD4+, CD8+) and the lymphocyte proliferative responses to mitogens (PHA, Con A, PWM), in the environment of fetal calf serum (FCS) were examined in 16 normal primigravidas in the third trimester of pregnancy and in 15 healthy nonpregnant women. In normal pregnant women significantly lower absolute and percentage numbers of CD3+ and CD4+ T cells and almost twice reduced CD4+/CD8+ ratio were found, in comparison with nonpregnant subjects. Despite the shifts among particular T lymphocyte subsets in the peripheral blood, non disorders were found in the lymphocyte proliferative responses to mitogens in normal pregnancy.
在胎牛血清（FCS）环境中，对16例妊娠晚期的正常初产妇和15例健康未孕妇女的T淋巴细胞亚群（CD3 +、CD4 +、CD8 +）以及淋巴细胞对有丝分裂原（PHA、Con A、PWM）的增殖反应进行了检测。与未孕受试者相比，正常孕妇的CD3 +和CD4 + T细胞的绝对数量和百分比显著降低，CD4 + / CD8 +比值几乎降低了一半。尽管外周血中特定T淋巴细胞亚群发生了变化，但正常妊娠中淋巴细胞对有丝分裂原的增殖反应未发现异常。
